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Publikationen/Publications

2024

591. Fähnrich A, Gasimova Z, Maluje Y, Ott F, Sievert H, Fliedner S, Reimer N, Künstner A, Gebauer N, Kebenko M, von Bubnoff N, Kirfel J, Sailer VW, Röcken C, Konukiewitz B, Klapper W, Frydrychowicz A, Mogadas S, Huebner G, Busch H, Khandanpour C. Case report: Tenosynovial giant cell tumor. Front Oncol. 2024 Sep 26;14:1445427. doi: 10.3389/fonc.2024.1445427. eCollection 2024.

590. Simon P, Behrens HM, Kristen A, Röcken C. Myocardial inflammatory cells in cardiac amyloidosis. Sci Rep. 2024 Oct 7;14(1):23313. doi: 10.1038/s41598-024-74289-5.

589. Ghadimi D, Fölster-Holst R, Blömer S, Ebsen M, Röcken C, Uchiyama J, Matsuzaki S, Bockelmann W. Intricate crosstalk between food allergens, phages, bacteria, and eukaryotic host cells of the gut-skin axis. Yale J Biol Med. 2024 Sep 30;97(3):309-324. eCollection 2024 Sep.

588. Röcken C. Definiton und Klassifikation der Amyloidosen. Pathogenese der Amyloidosen. In: Sommer C, Birklein F, Hund E (Hrsg.). Systemische ATTR-Amyloidosen - Hereditäre Amyloidneuropathien und andere Organmanifestationen. 3. Auflage UNI-MED, Bremen, 2024; S. 10-18; S. 46-50

587. Canetti D, Taylor GW, Lavatelli F, Röcken C. A report from the European Proteomics Amyloid Network (EPAN). Amyloid. 2024 Aug 22:1-3. doi: 10.1080/13506129.2024.2392185

586. Fincke VE, Steinbügl M, Chun HE, Nemes K, Mucha M, Loßner M, Dorn F, Gastberger K, Bühner S, Sill M, Kröncke T, Siebert R, Melchior P, Furtwängler R, Schlesner M, Vokuhl C, Röcken C, Johann PD, Frühwald MC. Clinical and molecular risk factors in extracranial malignant rhabdoid tumors - Towards an integrated model of high-risk tumors. Clin Cancer Res. 2024 Aug 9. doi: 10.1158/1078-0432.CCR-23-3489. Online ahead of print.

585. Fassan M, Kuwata T, Matkowskyj KA, Röcken C, Rüschoff J. Claudin-18.2 immunohistochemical evaluation in gastric and gastroesophageal junction adenocarcinomas to direct targeted therapy: a practical approach. Mod Pathol. 2024 Aug 2;37(11):100589. doi: 10.1016/j.modpat.2024.100589.

584. Röcken C. Clinical and translational research on cancer of the stomach and gastroesophageal junction: a pathologist’s view. Clin Transl Disc. 2024;4:e332. doi.org/10.1002/ctd2.332

583. Rüsing S, Welz L, Pfitzer C, Harris DM, Röcken C, Rosenstiel P, Nikolaus S, Tran F, Schreiber S, Aden K, Sievers LK. Decreased serum tryptophan and severe ulcerative damage of colon mucosa identify inflammatory bowel disease patients with high risk of CMV colitis. Clin Transl Gastroenterol. 2024 Jun 27. doi: 10.14309/ctg.0000000000000731. Online ahead of print.

582. Ahmeti H, Kiese D, Freitag-Wolf S, Kalab M, Röcken C, Jansen O, Mehdorn M, Synowitz M. IDH1 mutation is associated with improved resection rates, progression-free survival and overall survival in patients with anaplastic astrocytomas. J Neurooncol. 2024 Jun 23. doi: 10.1007/s11060-024-04743-x. Online ahead of print.

581. Ulase D, Behrens HM, Röcken C. Stroma-AReactive Invasion Front Areas (SARIFA) in adenocarcinomas of the stomach and gastrooesophageal junction predict poor survival: a validation study. Virchows Arch. 2024 May 15. doi: 10.1007/s00428-024-03826-4.

580. Ellrichmann M, Schulte B, Conrad CC, Schoch S, Bethge J, Seeger M, Huber R, Goeb M, Arlt A, Nikolaus S, Röcken C, Schreiber S. Contrast enhanced endoscopic ultrasound detects early therapy response following anti-TNF-therapy in patients with ulcerative colitis. J Crohns Colitis. 2024 Mar 8:jjae034. doi: 10.1093/ecco-jcc/jjae034.

579. Fischbach W, Bornschein J, Hoffmann JC, Koletzko S, Link A, Macke L, Malfertheiner P, Schütte K, Selgrad DM, Suerbaum S, Schulz C; Collaborators. Update S2k-Guideline Helicobacter pylori and gastroduodenal ulcer disease of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS). Z Gastroenterol. 2024 Feb;62(2):261-321. doi: 10.1055/a-2181-2225.

578. Guo Y, Endmayr V, Zekeridou A, McKeon A, Leypoldt F, Hess K, Kalinowska-Lyszczarz A, Klang A, Pakozdy A, Höftberger E, Hametner S, Haider C, De Simoni D, Peters S, Gelpi E, Röcken C, Oberndorfer S, Lassmann H, Lucchinetti CF, Höftberger R. New insights in neuropathology and pathogenesis of autoimmune glial fibrillary acidic protein meningoencephalomyelitis. Acta Neuropathol. 2024 Feb 3;147(1):31. doi: 10.1007/s00401-023-02678-7.

577. Dargvainiene J, Jensen-Kondering U, Bender B, Berg D, Brüggemann N, Flüh C, Markewitz R, Neumann A, Röben B, Röcken C, Royl G, Schulte C, Wandinger KP, Weiler C, Margraf NG, Kuhlenbäumer G. Aβ38 and Aβ43 do not differentiate between Alzheimer's disease and cerebral amyloid angiopathy. Ann Clin Transl Neurol. 2024 Jan 7. doi: 10.1002/acn3.51987. Online ahead of print.

576. Barreton G, Gaiser T, Hofheinz RD, Horst D, Lorenzen S, Möhler M, Röcken C, Schirmacher P, Stahl M, Tiemann K, Thuss-Patience P, Lordick F. Standardized and quality-assured predictive PD-L1 testing in the upper gastrointestinal tract. Pathologie (Heidelb). 2024 Feb;45(1):51-58. doi: 10.1007/s00292-023-01215-3

575. Ghadimi D, Fölster-Holst R, Ebsen M, Röcken C, Dörfer C, Uchiyama J, Matsuzaki S, Bockelmann W. Exploring the Interplay between Nutrients, Bacteriophages, and Bacterial Lipases in Host- and Bacteria-mediated Pathogenesis. Endocr Metab Immune Disord Drug Targets. 2024;24(8):930-945. doi: 10.2174/0118715303257321231024094904.

574. Bernhardt M, Behrens HM, Krüger S, Röcken C. Exploration of the tumor biological significance of PCLO in gastric cancer - Results from a large Central European cohort. Pathobiology. 2024;91(3):187-195. doi: 10.1159/000534889. Epub 2023 Nov 7.

573. Ungericht M, Groaz V, Messner M, Schuetz T, Brunelli L, Zaruba MM, Lener D, Stocker E, Bauer A, Kroiss AS, Mayr A, Röcken C, Poelzl G. Correlation of 99mTc-DPD bone scintigraphy with histological amyloid load in patients with ATTR cardiac amyloidosis. Amyloid. 2024 Mar;31(1):22-31. doi: 10.1080/13506129.2023.2239986.

572. Huebbe P, Bilke S, Rueter J, Schloesser A, Campbel G, Glüer CC, Lucius R, Röcken C, Tholey A, Rimbach G. Human APOE4 protects high-fat and high-sucrose diet fed targeted replacement mice against fatty liver disease compared to APOE3. Aging Dis. 2023 Jun 12. doi: 10.14336/AD.2023.0530.

2023

571. Ungericht M, Wanschitz J, Kroiss AS, Röcken C, Schuetz T, Messner M, Zaruba MM, Loescher W, Poelzl G. Amyloid myopathy – expanding the clinical spectrum of transthyretin amyloidosis: case report and literature review. J Nucl Cardiol. 2023 Aug;30(4):1420-1426. doi: 10.1007/s12350-022-02990-x.

570. Barreton G, Gaiser T, Hofheinz RD, Horst D, Lorenzen S, Möhler M, Röcken C, Schirmacher P, Stahl M, Tiemann K, Thuss-Patience P, Lordick F. Standardized and quality-assured predictive PD-L1 testing in the upper gastrointestinal tract. J Cancer Res Clin Oncol. 2023 Nov;149(17):16231-16238. doi: 10.1007/s00432-023-05180-5.

569. Muti HS, Röcken C, Behrens HM, Löffler CML, Reitsam NG, Grosser B, Märkl B, Stange DE, Jiang X, Velduizen GP, Truhn D, Ebert MP, Grabsch HI, Kather JN. Deep learning trained on lymph node status predicts outcome from gastric cancer histopathology: a retrospective multicentric study. Eur J Cancer. 2023 Sep 12;194:113335. doi: 10.1016/j.ejca.20 23.113335

568. Abdullazade S, Behrens HM, Krüger S, Haag J, Röcken C. MDM2 amplification is rare in gastric cancer. Virchows Arch. 2023 Oct 11. doi: 10.1007/s00428-023-03674-8. Online ahead of print.

567. Ahmeti H, Caliebe A, Trigui N, Alati I, Röcken C, Jansen O, Synowitz M, Mehdorn MH. Surgical approach for convexity meningiomas: An analysis of the preoperative clinical signs, radiological features and surgical outcomes of these tumors. Clin Neurol Neurosurg. 2023 Oct;233:107914. doi: 10.1016/j.clineuro.2023.107914. Epub 2023 Jul 27.

566. Daunke T, Beckinger S, Rahn S, Krüger S, Heckl S, Schäfer H, Wesch D, Pilarsky C, Eckstein M, Hartmann A, Röcken C, Wandmacher AM, Sebens S. Analysis of the immune checkpoint regulator PD-L1 in the tumor-stroma interplay in pancreatic ductal adenocarcinoma. Front Immunol. 2023 Jun 28;14:1157397. doi: 10.3389/fimmu.2023.1157397. eCollection 2023.

565. Richter F, Henssen C, Steiert T, Meissner T, Mehdorn AS, Röcken C, Franke A, Egberts JH, Becker T, Sebens S, Forster M. Liquid biopsy for therapy monitoring in esophageal cancer. Int J Mol Sci. 2023 Jun 26;24(13):10673. doi: 10.3390/ijms241310673.

564. Marchi F, Kessler C, Distefano D, Terzi di Bergamo L, Fumagalli L, Averaimo M, Crupi E, Bergamini F, Melli G, Stussi G, Rossi D, Gobbi C, Ripellino P, Pravatà E, Kuhlen DE, Röcken C, Scarone P, Gerber B, Condoluci A. Prevalence of amyloid in ligamentum flavum of patients with lumbar spinal stenosis. Amyloid. 2023 Jul 11:1-8. doi: 10.1080/13506129.2023.2230516

563. Treitz C, Müller-Marienburg N, Meliß RR, Urban P, Axmann HD, Siebert F, Becker K, Martens K, Behrens HM, Gericke E, Tholey A, Röcken C. ATTR- and AFib amyloid - two different types of amyloid in the annular ligament of trigger finger. Amyloid. 2023 Jun 23:1-13. doi: 10.1080/13506129.2023.2226298.

562. Griger J, Widholz SA, Jesinghaus M, de Andrade Krätzig N, Lange S, Engleitner T, Montero JJ, Zhigalova E, Öllinger R, Suresh V, Winkler W, Lier S, Baranov O, Trozzo R, Ben Khaled N, Chakraborty S, Yu J, Konukiewitz B, Steiger K, Pfarr N, Rajput A, Sailer D, Keller G, Schirmacher P, Röcken C, Fagerstedt KW, Mayerle J, Schmidt-Supprian M, Schneider G, Weichert W, Calado DP, Sommermann T, Klöppel G, Rajewsky K, Saur D, Rad R. An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets. Cancer Cell. 2023;41(7):1327-1344.e10. doi: 10.1016/j.ccell.2023.06.001

561. Steiert TA, Parra G, Gut M, Arnold N, Trotta JR, Tonda R, Moussy A, Gerber Z, Abuja PM, Zatloukal K, Röcken C, Folseraas T, Grimsrud MM, Vogel A, Goeppert B, Roessler S, Hinz S, Schafmayer C, Rosenstie P, Deleuze JF, Gut IG, Franke A, Forster M. A critical spotlight on the paradigms of FFPE-DNA sequencing. Nucleic Acids Res. 2023;51(14):7143-7162. doi: 10.1093/nar/gkad519.

560. Ulase D, Behrens HM, Krüger S, Heckl S, Ebert U, Becker T, Röcken C. LAG3 in gastric cancer: it’s complicated. J Cancer Res Clin Oncol. 2023;149(12):10797-10811. doi: 10.1007/s00432-023-04954-1

559. Kuhlen M, Kunstreich M, Lessel L, Wudy SA, Holterhus PM, Vokuhl C, Jüttner E, Röcken C, Seitz G, Slavetinsky C, Fuchs J, Schewe D, Claus R, Pascal DJ, Frühwald MC, Vorwerk P, Redlich A. Refractory and Relapsed Paediatric ACT in the MET Studies – A Challenging Situation Necessitating Novel Diagnostic and Therapeutic Concepts. EJC Paediatric Oncology. May 23, 2023. doi.org/10.1016/j.ejcped.2023.100015

558. Veldhuizen GP, Röcken C, Behrens HM, Cifci D, Muti HS, Yoshikawa T, Arai T, Oshima T, Tan P, Ebert MP, Pearson AT, Calderaro J, Grabsch HI, Kather JN. Deep learning-based subtyping of gastric cancer histology predicts clinical outcome: a multi-institutional retrospective study. Gastric Cancer. 2023 Jun 3. doi: 10.1007/s10120-023-01398-x

557. Tundidor I, Seijo-Vila M, Blasco-Benito S, Rubert-Hernández M, Adámez S, Andradas C, Manzano S, Álvarez-López I, Sarasqueta C, Villa-Morales M, González-Lois C, Ramírez-Medina E, Almoguera B, Sánchez-López AJ, Bindila L, Hamann S, Arnold N, Röcken C, Heras-Murillo I, Sancho D, Moreno-Bueno G, Caffarel MM, Guzmán M, Sánchez C, Pérez-Gómez E. Identification of fatty acid amide hydrolase as a new metastasis suppressor in breast cancer. Nat Commun. 2023 May 30;14(1):3130. doi: 10.1038/s41467-023-38750-9

556. Beckinger S, Daunke T, Aldag L, Krüger S, Heckl S, Wesch D, Schäfer H, Röcken C, Rahn S, Sebens S. Impact of hepatic myofibroblasts on expression of the immune checkpoint regulator PD-L1 and its targeting in liver metastasis of pancreatic ductal adenocarcinoma. Front Oncol. 2023 May 3;13:1160824. doi: 10.3389/fonc.2023.1160824. eCollection 2023.

555. Purrucker JC, Röcken C, Reuss D. Iatrogenic cerebral amyloid angiopathy rather than sporadic CAA in younger adults with lobar intracerebral haemorrhage. Amyloid. 2023 May 15:1-3. doi: 10.1080/13506129.2023.2212394. Online ahead of print.

554. Fischbach  W, Bornschein J, Hoffmann JC, Koletzko S, Link A, Macke L, Malfertheiner P, Schütte K, Selgrad  DM, Suerbaum S, Schulz C, Beyer A, Bossaller L, Bufler P, Daum S, Denzer U, Dichtl K, Ebert M, Eck M, Gerhard M, Gross M, Kandulski A, Labenz J, Thi TGL, Lübbert C, Madisch A, Mainz D, Miehlke S, Mönnikes H, Peitz U, Posovszky C, Röcken C, Schepp W, Sigal M, Spinner C, Storr MA, Terjung B, Venerito M, Voigtländer T. Aktualisierte S2k-Leitlinie Helicobacter pylori und gastroduodenale Ulkuskrankheit der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) – Juli 2022 – AWMF-Registernummer: 021–001. Z Gastroenterol. 2023 May;61(5):544-606. doi: 10.1055/a-1975-0414. Epub 2023 May 5.

553. Huhndorf M, Röcken C, Flüh C, Weiler C, Kuhlenbäumer G, Tegeler N, Schacht H, Neumann A, Margraf NG, Jensen-Kondering U. Frequency of deep-seated cerebral microbleeds in patients with lobar hemorrhages and histopathological evidence for cerebral amyloid angiopathy. Front Neurol. 2023 Apr 12;14:1146737. doi: 10.3389/fneur.2023.1146737. eCollection 2023.

552. Ghadimi D, Fölster-Holst R, Röcken C, Kaatsch HJ, Ebsen M, Tournebize R, Bockelmann W. Endogenous ethanol-producing bacteria interference in pathogen-host crosstalk. Endocr Metab Immune Disord Drug Targets. 2023 Mar 30. doi: 10.2174/1871530323666230330111355. Online ahead of print.

551. Siemsen W, Halske C, Behrens HM, Krüger S, Becker-Pauly C, Röcken C. The putative pleiotropic functions of meprin b in gastric cancer. Gastric Cancer. 2023 Mar 28. doi: 10.1007/s10120-023-01385-2. Online ahead of print.

550. Pries K, Krüger S, Heckl S, Behrens HM, Röcken C. SMARCA4 and SMARCE1 in gastric cancer: correlation with ARID1A, and microsatellite stability, and SMARCE1/ERBB2 co-amplification. Cancer Med. 2023 May;12(9):10423-10437. doi: 10.1002/cam4.5776

549. Holm B, Barsuhn S, Behrens HM, Krüger S, Röcken C. The tumor biological significance of RNF43 and LRP1B in gastric cancer is complex and context-dependent. Sci Rep. 2023 Feb 23;13(1):3191. doi: 10.1038/s41598-023-30294-8.

548. Ahmeti H, Caliebe A, Röcken C, Jansen O, Mehdorn MH, Synowitz M. Impact of peritumoral brain edema on pre- and postoperative clinical conditions and on long-term outcomes in patients with intracranial meningiomas. Eur J Med Res. 2023 Jan 21;28(1):40. doi: 10.1186/s40001-022-00962-y

547. Jensen-Kondering U, Margraf NG, Weiler C, Leypoldt F, Maetzler W, Philippen S, Bartsch T, Flueh C, Röcken C, Möller B, Royl G, Neumann A, Brüggemann N, Röben B, Schulte C, Bender B, Berg D, Kuhlenbäumer G. Characterizing mixed location hemorrhages/microbleeds with CSF markers. Int J Stroke. 2023 Feb 1:17474930231152124. doi: 10.1177/17474930231152124.

546. Geismann C, Hauser C, Grohmann F, Schneeweis C, Bölter N, Gundlach JP, Schneider G, Röcken C, Meinhardt C, Schäfer H, Schreiber S, Arlt A. NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer. Cell Death Dis. 2023 Jan 3;14(1):3. doi: 10.1038/s41419-022-05535-9.

545. Kock am Brink M, Dunst LS, Behrens HM, Krüger S, Becker T, Röcken C. Intratumoral heterogeneity affects tumor regression and Ki67 proliferation index in perioperatively treated gastric carcinoma. Br J Cancer. 2023 Jan;128(2):375-386. doi: 10.1038/s41416-022-02047-3. Epub 2022 Nov 8.

544. Le HD, Pflaum T, Sari S, Brettschneider F, Nikolaus S, Lassen A, Szymczak S, Kormilez D, Rosenstiel P, Schreiber S, Aden K, Röcken C. Interobserver reliability of the Nancy index for ulcerative colitis: An assessment of the practicability and ease of use in a single-centre real-world setting. J Crohns Colitis. 2023 Apr 3;17(3):389-395. doi: 10.1093/ecco-jcc/jjac146

543. Röcken C. Predictive biomarkers in gastric cancer. J Cancer Res Clin Oncol. 2023 Jan;149(1):467-481.doi: 10.1007/s00432-022-04408-0


2022

542. Kuhlen M, Kunstreich M, Lessel L, Schneider DT, Brecht IB, Schewe D, Seitz G, Holterhus PM, Wudy SA, Röcken C, Vokuhl C, Johann P, Frühwald MC, Vorwerk P, Redlich A. Outcome for pediatric adreno-cortical tumors is best predicted by the COG stage and five-item microscopic score-report from the German MET studies. Cancers (Basel). 2022 Dec 30;15(1):225. doi: 10.3390/cancers15010225.

541. Thimm A, Oubari S, Hoffmann J, Carpinteiro A, Papathanasiou M, Luedike P, Kessler L, Rischpler C, Röcken C, Kleinschnitz C, Hagenacker T. A novel TTR mutation (p.Ala65Val) underlying hereditary transthyretin (ATTRv) amyloidosis with mixed cardiac and neuropathic phenotype. BMC Neurol. 2022 Dec 9;22(1):469. doi: 10.1186/s12883-022-02952-3.

540. Steinebrei M, Gottwald J, Baur J, Röcken C, Hegenbart U, Schönland SO, Schmidt M. Cryo-EM structure of an ATTRwt amyloid fibril from systemic non-hereditary transthyretin amyloidosis. Nat Commun. 2022 Oct 27;13(1):6398. doi: 10.1038/s41467-022-33591-4. PMID: 36302762

539. Mehdorn AS, Gemoll T, Busch H, Kern K, Beckinger S, Daunke T, Kahlert C, Uzunoglu FG, Hendricks A, Buertin F, Wittel UA, Sunami Y, Röcken C, Becker T, Sebens S. Biomarkers in liquid biopsies for prediction of early liver me-tastases in pancreatic cancer. Cancers (Basel). 2022 Sep 22;14(19):4605. doi: 10.3390/cancers14194605.

538. von Stillfried S, Freeborn B, Windeck S, Boor P; DeRegCOVID und NATON. Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin. Pathologie (Heidelb). 2022 Sep 16;1-5. doi: 10.1007/s00292-022-01117-w.

537. Jensen-Kondering U, Flüh C, Röcken C, Margraf NG. Probable cerebral amyloid angiopathy diagnosed on plain CT. Neurol Sci. 2022 Aug 16. doi:10.1007/s10072-022-06330-2

536. Hinsenkamp I, Köhler JP, Flächsenhaar C, Hitkova I, Eberhart Meessen S, Gaiser T, Wieland Z, Weiss C, Röcken C, Mowat M, Quante M, Taxauer K, Mejias Luque R, Gerhard M, Vogelmann R, Meindl-Beinker N, Ebert M, Burgermeister E. Functional antagonism between CagA and DLC1 in gastric cancer Cell Death Discov. 2022 Aug 13;8(1):358. doi: 10.1038/s41420-022-01134-x.

535. Bamberg LV, Heigwer F, Wandmacher AM, Singh A, Betge J, Rindtorff N, Werner J, Josten J, Skabkina OV, Hinsenkamp I, Erdmann G, Röcken C, Ebert MP, Burgermeister E, Zhan T, Boutros M. Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors. Int J Cancer. 2022 Jun 6. doi: 10.1002/ijc.34155. Online ahead of print.

534. Gundlach JP, Kerber J, Hendricks A, Bernsmeier A, Halske C, Becker T, Röcken C, Braun F, Sebens S, Heits N. Paracrine interaction of cholangiocellular carcinoma with cancer-associated fibroblasts and Schwann cells impact cell migration. J Clin Med. 2022, 11(10), 2785; https://doi.org/10.3390/jcm11102785

533. Schmidt M, Yilmaz A, Bietenbeck M, Schilling M, Röcken C, Schmidt HH. de novo hATTR amyloidosis after domino transplantation of a donor's liver: a case report for the use of Patisiran. Z Gastroenterol. 2022 May 9. doi: 10.1055/a-1735-3795. Online ahead of print.

532. Anker S, Hinderhofer K, Baur J, Haupt C, Röcken C, Beimler J, Zeier M, Weiler M, Wühl E, Kimmich C, Schönland S, Hegenbart U. Lysozyme amyloidosis-a report on a large German cohort and the characterisation of a novel amyloidogenic lysozyme gene variant. Amyloid. 2022 May 9:1-10. doi: 10.1080/13506129.2022.2072198. Online ahead of print.

531. von Stillfried S, Bülow RD, Röhrig R, Boor P, German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators.  First report from the German COVID-19 autopsy registry. Lancet Reg Health Eur. 2022 Feb 18;15:100330. doi: 10.1016/j.lanepe.2022.100330. eCollection 2022 Apr.

530. Lutter G, Puehler T, Röcken C, Both M. Magnetic resonance imaging-based diagnosis of aortitis preceding development of a thoracic aneurysm in a patient with giant cell arteritis: a case report. Eur Heart J Case Rep. 2022 Apr 12;6(4):ytac152. doi: 10.1093/ehjcr/ytac152. eCollection 2022 Apr. PMID: 3550586

529. Ghadimi D, Ebsen M, Röcken C, Fölster-Holst R, Groessner-Schreiber B, Dörfer C, Bockelmann W. Oral mucosal in vitro cell culture model to study the effect of Fructilactobacillus phage on the crosstalk between food components and oral microbiota. Endocr Metab Immune Disord Drug Targets. 2022 Apr 8. doi: 10.2174/1871530322666220408215101

528. Jonigk D, Werlein C, Acker T, Aepfelbacher M, Amann KU, Baretton G, Barth P, Bohle RM, Büttner A, Büttner R, Dettmeyer R, Eichhorn P, Elezkurtaj S, Esposito I, Evert K, Evert M, Fend F, Gaßler N, Gattenlöhner S, Glatzel M, Göbel H, Gradhand E, Hansen T, Hartmann A, Heinemann A, Heppner FL, Hilsenbeck J, Horst D, Kamp JC, Mall G, Märkl B, Ondruschka B, Pablik J, Pfefferle S, Quaas A, Radbruch H, Röcken C, Rosenwald A, Roth W, Rudelius M, Schirmacher P, Slotta-Huspenina J, Smith K, Sommer L, Stock K, Ströbel P, Strobl S, Titze U, Weirich G, Weis J, Werner M, Wickenhauser C, Wiech T, Wild P, Welte T, von Stillfried S, Boor P.Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies? Virchows Arch. 2022 Aug;481(2):139-159. doi: 10.1007/s00428-022-03319-2.

527. Peuker K, Strigli A, Tauriello DVF, Hendricks A, von Schönfels W, Burmeister G, Brosch M, Herrmann A, Krüger S, Nitsche S, Južnić L, Geissler MM, Hiergeist A, Gessner A, Wirbel J, Ponnudurai RP, Voogdt CGP, Tunger A, Wehner R, Stange DE, Weitz J, Aust DE, Baretton G, Schmitz M, Röcken C, Hampe J, Hinz S, Zeller G, Chacakis T, Schafmayer C, Batlle E, Zeissig S. Integration of microbial signals by myeloid calcineurin controls anti-tumor immunity in colorectal cancer. Immunity. 2022 Apr 12;55(4):701-717.e7. doi: 10.1016/j.immuni.2022.03.008.

526. von Stillfried S, Bülow RD, Röhrig R, Myebohm P, Boor P, German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report. Crit Care. 2022 Mar 28;26(1):83. doi: 10.1186/s13054-022-03945-x.

525. Margraf HN, Jensen-Kondering U, Weiler C, Leypoldt F, Maetzler W, Philippen S, Bartsch T, Flüh C, Röcken C, Möller B, Royl G, Neumann A, Brüggemann N, Roeben B, Schulte C, Bender B, Berg D, Kuhlenbäumer G. Cerebrospinal fluid biomarkers in cerebral amyloid angiopathy: New data and quantitative meta-analysis. Front Aging Neurosci. 2022. Im Druck.

524. Ibrahim NK, Eraky A, Eggers J, Steiert TA, Sebens S, Jünemann KP, Hendricks A, Bang C, Stanulla M, Franke A, Hamann C, Röcken C, Arnold N, Hinze L, Forster M. Detection of Cancer Mutations by Urine Liquid Biopsy as a Potential Tool in the Clinical Management of Bladder Cancer Patients. Cancers 2022, 14(4), 969; https://doi.org/10.3390/cancers14040969

523. Schrumpf T, Behrens HM, Haag J, Krüger S, Röcken C. FGFR2 overexpression and compromised survival in diffuse-type gastric cancer in a large central European cohort. PLoS One. 2022 Feb 15;17(2):e0264011. doi: 10.1371/journal.pone.0264011. eCollection 2022.

522. Mattig I, Heidecker B, Tschöpe C, Messroghli D, Eurich D, Kleefeld F, Gaedeke J, Stenzel W, Schmidt HH, Röcken C, Knebel F, Hahn K. Progressive Hereditary Transthyretin-Related Amyloidosis (ATTRv) Aggravated by ATTR Wild-Type and Complement Activation. J Neuropathol Exp Neurol. 2022 Jan 29:nlab138. doi: 10.1093/jnen/nlab138.

521. Ziemer A, Heß K, Stuhlmann-Laeisz C, Röcken C. Führender Befund lag in der Lunge. Bericht des Instituts für Pathologie des Universitätsklinikums Schleswig-Holstein (UKSH), Campus Kiel, über die dort durchgeführten klinischen Obduktionen. Schleswig-Holsteinisches Ärzteblatt. 2022; 75 (1):28-29

520. Gürgen D, Conrad T, Becker M, Sebens S, Röcken C, Hoffmann J, Langhammer S. Breaking the crosstalk of the cellular tumorigenic network by low-dose combination therapy in lung cancer patient-derived xenografts.Commun Biol. 2022 Jan 17;5(1):59. doi: 10.1038/s42003-022-03016-5.

519. Welz L, Kakavand N, Hang X, Laue G, Ito G, Gomes Silva M, Plattner C, Mishra N, Tengen F, Ogris C, Jesinghaus M, Wottawa F, Arnold P, Kaikkonen L, Stengel S, Tran F, Das S, Kaser A, Trajanoski Z, Blumberg R, Röcken C, Saur D, Tschurtschenthaler M, Schreiber S, Rosenstiel P, Aden K. Epithelial XBP1 coordinates p53-driven DNA damage responses and suppression of intestinal carcinogenesis. Gastroenterology. 2022 Jan;162(1):223-237.e11. doi: 10.1053/j.gastro.2021.09.057

518. Kramp LJ, Mathiak M, Behrens HM, Schäfer F, van Mackenbergh M, Röcken C. The age-specific differences in histopathological tumor characteristics and TNM classification of breast carcinomas in Quality assured Mamma Diagnostic (QuaMaDi) Program in the State of Schleswig-Holstein in Germany. J Cancer Res Clin Oncol. 2021 Oct 27. doi: 10.1007/s00432-021-03841-x. Online ahead of print.

2021

517. Rosenkranz SC, Häußler V, Kolster M, Willing A, Matschke J, Röcken C, Stürner K, Leypoldt F, Tolosa E, Friese MA. Treating sarcoidosis-associated progressive multifocal leukoencephalopathy with infliximab. Brain Commun. 2021 Dec 16;4(1):fcab292. doi: 10.1093/braincomms/fcab292. eCollection 2022 Feb.

516. Treitz C, Gottwald J, Gericke E, Urban P, Meliß RR, Axmann HD, Siebert F, Becker K, Tholey A, Röcken C. Quantitative proteome profiling provides evidence of an activation of the complement cascade in ATTR amyloidosis. Amyloid. 2021 Dec 16:1-8. doi: 10.1080/13506129.2021.2015316

515. Hoffmann A, Behrens HM, Heckl S, Krüger S, Röcken C. Neoadjuvant/perioperative treatment affects spatial distribu-tion and densities of tumor associated neutrophils and CD8+ lymphocytes in gastric cancer. J. Pers. Med. 2021, 11(11), 1184; https://doi.org/10.3390/jpm11111184

514. Ahmeti H, Jüttner E, Röcken C, Jansen O, Synowitz M. Differential diagnosis in hypophysitis: first report on a spindle cell rhabdomyosarcoma of the pituitary gland. J Neurol Surg A Cent Eur Neurosurg. 2021 Nov 15. doi: 10.1055/s-0041-1735857.

513. Benson MD, Berk JL, Dispenzieri A, Damy T, Gillmore JD, Hazenberg BP, Lavatelli F, Picken MM, Röcken C, Schönland S, Ueda M, Westermark P. Tissue biopsy for the diagnosis of amyloidosis: experience from some centers. Amyloid. 2021 Nov 12:1-6. doi: 10.1080/13506129.2021.1994386

512. Röcken C, Amallraja A, Halske C, Opasic L, Traulsen A, Behrens HM, Krüger S, Liu A, Haag J, Egberts JH, Rosenstiel P, Meißner T. Multiscale heterogeneity in gastric adenocarcinoma evolution is an obstacle to precision medicine. Genome Med. 2021 Nov 8;13(1):177. doi: 10.1186/s13073-021-00975-y.

511. Heckl SM, Kercher L, Abdullazade S, Schneider C, Krüger S, Behrens HM, Sebens S, Schäfer H, Schreiber S, and Röcken C. Insulin receptor in pancreatic cancer – crown witness in cross examination. Cancers (Basel). 2021 Oct 5;13(19):4988. doi: 10.3390/cancers13194988.

510. Ahmeti H, Borzikowsky C, Hollander D, Röcken C, Jansen O, Synowitz M, Mehdorn M. Risks and neurological benefits of meningioma surgery in elderly patients compared to young patients. J Neurooncol. 2021 Sep 1. doi: 10.1007/s11060-021-03832-5.

509. Ghadimi D, Frahm SO, Röcken C, Ebsen M, Schwiertz A, Fölster-Holst R, Bockelmann W, Heller KJ. Effects of ad libitum free-choice access to freshly squeezed domestic white asparagus juice on intestinal microbiota composition and universal biomarkers of immuno-metabolic homeostasis and general health in middle-aged female and male C57BL/6 mice. Endocr Metab Immune Disord Drug Targets. 2021 Aug 30. doi: 10.2174/1871530321666210830150620.

508. Vvedenskaya O, Rose TD, Knittelfelder O, Palladini A, Wodke JAH, Schumann K, Ackerman JM, Wang Y, Has C, Brosch M, Thangapandi VR, Buch S, Züllig T, Hartler J, Köfeler HC, Röcken C, Coskun Ü, Klipp E, von Schoenfels W, Gross J, Schafmayer C, Hampe J, Pauling JK, Shevchenko A. NAFLD Stratification by Liver Lipidomics. J Lipid Res. 2021 Aug 9:100104. doi: 10.1016/j.jlr.2021.100104.

507. Gottwald J, Röcken C. The amyloid proteome: A systematic review and proposal of a protein classification system. Crit Rev Biochem Mol Biol. 2021 Oct;56(5):526-542. DOI: 10.1080/10409238.2021.1937926. Epub 2021 Jul 27

506. Gundlach P, Hauser C, Schlegel FM, Willms A, Halske C, Röder C, Krüger S, Röcken C, Becker T, Kalthoff H, Trauzold A. Prognostic significance of High mobility group A2 (HMGA2) in pancreatic ductal adenocarcinoma: Malignant functions of cytoplasmatic HMGA2 expression. J Cancer Res Clin Oncol. 2021 Jul 24. doi: 10.1007/s00432-021-03745-w

505. Heckl SM, Mau F, Senftleben A, Daunke T, Beckinger S, Abdullazade S, Schreiber S, Röcken C, Sebens S, Schäfer H. Programmed Death-Ligand 1 (PD-L1) Expression Is Induced by Insulin in Pancreatic Ductal Adenocarcinoma Cells Pointing to Its Role in Immune Checkpoint Control. Med Sci (Basel). 2021 Jun 25;9(3):48. doi: 10.3390/medsci9030048.

504. Staubach P, Koch AK, Langhorst J, Schreiber S, Röcken C, Helwig U. Expression of the fructose transporter GLUT5 in patients with fructose malabsorption. Z Gastroenterol. 2021 Jun;59(6):531-539. doi: 10.1055/a-1156-4386

503. Schürmann J, Gottwald J, Rottenaicher G, Tholey A and Röcken C. MALDI Mass Spectrometry Imaging unravels organ- and amyloid-type specific peptide signatures in pulmonary and gastrointestinal amyloidosis. Proteomics Clin Appl. 2021 Jun 1:e2000079. doi: 10.1002/prca.202000079

502. Röcken C. Karzinome unklarer Primärlokalisation - Molekulare Diagnostik und „liquids“: eine Standortbestimmung. Der Onkologe. 2021; 27: 651–657. DOI: 10.1007/s00761-021-00963-2

501. Lux A, Gottwald J, Behrens HM, Daniel C, Amann K, Röcken C. Complement 9 in amyloid deposits. Amyloid. 2021 Sep;28(3):199-208. doi: 10.1080/13506129.2021.1932799

500. Zheng T, Ellinghaus D, Juzenas S, Cossais F, Burmeister G, Mayr G, Jørgensen IF, Teder-Laving M, Skogholt AH, Chen S, Strege PR, Ito G, Banasik K, Becker T, Bokelmann F, Brunak S, Buch S, Clausnitzer H, Datz C; DBDS Consortium, Degenhardt F, Doniec M, Erikstrup C, Esko T, Forster M, Frey N, Fritsche LG, Gabrielsen ME, Gräßle T, Gsur A, Gross J, Hampe J, Hendricks A, Hinz S, Hveem K, Jongen J, Junker R, Karlsen TH, Hemmrich-Stanisak G, Kruis W, Kupcinskas J, Laubert T, Rosenstiel PC, Röcken C, Laudes M, Leendertz FH, Lieb W, Limperger V, Margetis N, Mätz-Rensing K, Németh CG, Ness-Jensen E, Nowak-Göttl U, Pandit A, Pedersen OB, Peleikis HG, Peuker K, Rodriguez CL, Rühlemann MC, Schniewind B, Schulzky M, Skieceviciene J, Tepel J, Thomas L, Uellendahl-Werth F, Ullum H, Vogel I, Volzke H, von Fersen L, von Schönfels W, Vanderwerff B, Wilking J, Wittig M, Zeissig S, Zobel M, Zawistowski M, Vacic V, Sazonova O, Noblin ES; 23andMe Research Team, Farrugia G, Beyder A, Wedel T, Kahlke V, Schafmayer C, D'Amato M, Franke A. Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease Gut. 2021 Apr 22:gutjnl-2020-323868. doi: 10.1136/gutjnl-2020-323868

499. Hansen T, Titze U, Kulamadayil-Heidenreich NSA, Glombitza S, Tebbe JJ, Röcken C, Schulz B, Weise M, Wilkens L. First case of postmortem study in a patient vaccinated against SARS CoV2. Int J Infect Dis. 2021 Apr 16; S1201-9712(21)00364-7. doi: 10.1016/j.ijid.2021.04.053.

498. Gundlach JP, Schmidt S, Bernsmeier A, Günther R, Kataev V, Trentmann J, Schäfer JP, Röcken C, Becker T, Braun F. Indication of liver transplantation for hepatocellular carcinoma should be reconsidered in case of microvascular invasion and multilocular tumor occurrence. J Clin Med. 2021, 10(6), 1155; https://doi.org/10.3390/jcm10061155

497. Frank H, Röcken C. Spezielle Ursache einer Niereninsuffizienz nach Dominolebertransplantation. Nephrologe. 2021; doi.org/10.1007/s11560-021-00490-6

496. Ulase D, Behrens HM, Krüger S, Zeissig S, Röcken C. Gastric carcinomas with stromal B7-H3 expression have lower intratumoural CD8+ T cell density. Int. J. Mol. Sci. 2021; 22: 2129. https://doi.org/10.3390/ijms22042129

495. Schreiber S, Aden K, Bernardes JP, Conrad C, Tran F, Höper H, Volk V, Mishra N, Blase JI, Nikolaus S, Bethge J, Kühbacher T, Röcken C, Chen M, Cottingham I, Petri N, Rasmussen BB, Lokau J, Lenk L, Garbers C, Feuerhake F, Rose-John S, Waetzig GH, Rosenstiel P. Therapeutic IL-6 trans-signalling inhibition by olamkicept (sgp130Fc) in patients with active inflammatory bowel disease. Gastroenterology. 2021 Mar 2:S0016-5085(21)00467-4. doi: 10.1053/j.gastro.2021.02.062

494. Kuhl C, Walter P, Zimmer C, Mentzel HJ, Reimer P, Hausegger KA, Baretton G, Hoffmann RT, Heindel W, Düber C, Uder M, Nikolaou K, Antoch G; Vorstand der Deutschen Röntgengesellschaft e. V. (DRG):; Vorstand der Deutschen Gesellschaft für Neuroradiologie e. V. (DGNR); Vorstand der Gesellschaft für Pädiatrische Radiologie e. V. (GPR); Vorstand der Deutschen Gesellschaft für Interventionelle Radiologie und Minimalinvasive Therapie (DeGIR):; Präsidium der Österreichischen Röntgengesellschaft (ÖRG):; Vorstand der Deutschen Gesellschaft für Pathologie e. V. (DGP); Konferenz der Lehrstuhlinhaber für Radiologie e. V.: Positionspapier der DRG, DGNR, GPR, DeGIR, ÖRG und DGP zur Nutzung klinischer Daten für wissenschaftliche Zwecke. Rofo. 2021 Feb 2. doi: 10.1055/a-1352-9747. Online ahead of print


2020

493. Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P. Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells and plasmablasts as hallmarks of severe COVID-19 trajectories.Immunity. 2020 Dec 15;53(6):1296-1314.e9. doi: 10.1016/j.immuni.2020.11.017

492. Ghadimi D, de Vrese M, Ebsen M, Röcken C, Frahm SO, Zahlten J, Fölster-Holst R, Heller KJ, Bockelmann W. Study on the additive protective effect of PGLYRP3 and Bifidobacterium adolescentis Reuter 1963 on severity of DSS-induced colitis in Pglyrp3 knockout (Pglyrp3 -/-) and wild-type (WT) mice. Immunobiology. 2020 Nov 12;226(1):152028. doi: 10.1016/j.imbio.2020.152028

491. Ghadimi D, Nielsen A, Hassan MFY, Fölster-Holst R, Ebsen M, Frahm SO, Röcken C, de Vrese M, Heller KJ. Modulation of proinflammatory bacteria- and lipid-coupled intracellular signaling pathways in a transwell triple co-culture model by commensal Bifidobacterium animalis R101-8. Antiinflamm Antiallergy Agents Med Chem. 2020 Oct 29. doi: 10.2174/1871523019999201029115618.

490. Schoop I, Maleki SS, Behrens HM, Krüger S, Haag J, Röcken C. p53 immunostaining cannot be used to predict TP53 mutations in gastric cancer – Results from a large Central European cohort. Hum Pathol. 2020 Nov;105:53-66. doi: 10.1016/j.humpath.2020.09.006

489. Gundlach JP, Günther R, Both M, Trentmann J, Schäfer JP, Cremer J, Röcken C, Becker T, Braun F. Inferior vena cava constriction after liver transplantation is a severe complication which requires individually adapted treatment: Report of a single center experience. Ann Transplant. 2020 Aug 4;25:e925194. doi: 10.12659/AOT.925194.

488. Heckl S, Pellinghaus M, Behrens HM, Krüger S, Schreiber S, Röcken C. Questioning the IGF1 receptor’s assigned role in CRC – a case for rehabilitation? BMC Cancer. 2020 Jul 29;20(1):704. doi: 10.1186/s12885-020-07173-w.

487. Basset M, Hummedah K, Kimmich C, Veelken K, Dittrich T, Brandelik S, Kreuter M, Hassel J, Bosch N, Stuhlmann-Laeisz C, Blank N, Müller-Tidow C, Röcken C, Hegenbart U, Schönland S. Localized immunoglobulin light chain amyloidosis: novel insights including prognostic factors for local progression. Am J Hematol. 2020; 95:1158-1169. doi: 10.1002/ajh.25915

486. Thangapandi VR, Knittelfelder O, Brosch M, Patsenker E, Vvedenskaya O, Buch S, Hinz S, Hendricks A, Nati M, Herrmann A, Berg T, Matz-Soja M, Huse K, Klipp E, Pauling J, Wodke J, Coskun Ü, Aigner E, Datz C, von Schönfels W, Nehring S, Zeissig S, Röcken C, Dahl A, Chavakis T, Stickel F, Shevchenko A, Schafmayer C, Hampe J, Subramanian P. Loss of hepatic Mboat7 leads to liver fibrosis. Gut. 2020 Jun 26:gutjnl-2020-320853. doi: 10.1136/gutjnl-2020-320853

485. Brandelik SC, Heussel CP, Kauczor HU, Röcken C, Huber L, Kimmich C, Schönland SO, Hegenbart U, Nattenmüller J. Comprehensive analysis of radiological findings in chest CT scans in amyloidosis of the respiratory system. Eur J Radiol. 2020 Aug;129:109123. doi: 10.1016/j.ejrad.2020.109123.

484. Weidner P, Söhn M, Schroeder T, Helm L, Hauber V, Gutting T, Betge J, Röcken C, Rohrbacher FN, Pattabiraman VR, Bode JW, Seger R, Saar D, Nunes-Alves A, Wade RC, Ebert MPA, Burgermeister E. Myotubularin-related protein 7 activates peroxisome proliferator-activated receptor-gamma. Oncogenesis. 2020 Jun 10;9(6):59. doi: 10.1038/s41389-020-0238-8.

483. Heilmann T, Vondung F, Borzikowsky C, Krüger S, Elessawy M, Alkatout I, Wenners A, Bauer M, Klapper W, Röcken C, Maass N, Schem C, Trauzold A. Cytoplasmic levels of High mobility group A2 (HMGA2) determine survival prognoses in breast cancer patients.Int J Biol Markers. 2020 Jun;35(2):20-28. doi: 10.1177/1724600820917990.

482. Sandforth L, Ammar N, Dinges LA, Röcken C, Arlt A, Sebens S, Schäfer H. Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells. Cancers (Basel). 2020 Mar 3;12(3). pii: E581. doi: 10.3390/cancers12030581.

481. Jost M, Wehkamp U, Brasch J, Röcken C, Egberts F. Tumor an der Flanke. J Dtsch Dermatol Ges. 2020 Mar;18(3):271-273. doi: 10.1111/ddg.14038.

480. Beucke N, Wesch D, Oberg HH, Peters C, Bochem J, Weide B, Garbe C, Pawelec G, Sebens S, Röcken C, Hashimoto H, Löffler MW, Nocerino P, Kordasti S, Kabelitz D, Schilbach K, Wistuba-Hamprecht K. Pitfalls in the characterization of circulating and tissue-resident human γδ T cells. J Leukoc Biol. 2020;107:1097–1105. doi: 10.1002/JLB.5MA1219-296R.

479. Hendricks A, Rosenstiel P, Hinz S, Burmeister G, Röcken C, Boersch K, Schafmayer C, Becker T, Franke A, Forster M. Rapid response of stage IV colorectal cancer with APC/TP53/KRAS mutations to FOLFIRI and Bevacizumab combination chemotherapy: a case report of use of liquid biopsy. BMC Med Genet. 2020 Jan 3;21(1):3. doi: 10.1186/s12881-019-0941-5.

478. Schoop H, Bregenzer A, Halske C, Behrens HM, Krüger S, Egberts JH, Röcken C. Therapy resistance in neoadjuvantly treated gastric cancer and cancer of the gastroesophageal junction is associated with an increased expression of immune checkpoint inhibitors - comparison against a therapy naïve cohort. Transl Oncol. 2020 Feb;13(2):165-176. doi: 10.1016/j.tranon.2019.11.004

477. Albrecht T, Rausch M, Roessler S, Geissler V, Albrecht M, Halske C, Seifert C, Renner M, Singer S, Mehrabi A, Vogel MN, Pathil-Warth A, Czink E, Köhler B, Rupp C, Weiss KH, Springfeld C, Röcken C, Schirmacher P, Goeppert B. HER2 amplification is a low frequency driver with potential predictive value in gallbladder carcinoma. Virchows Arch. 2020 Jun;476(6):871-880. doi: 10.1007/s00428-019-02706-6.

476. Ghadimi D, Yoness Hassan MF, Fölster-Holst R, Röcken C, Ebsen M, de Vrese M, Heller KJ. Regulation of hepcidin/iron-signalling pathway interactions by commensal bifidobateria plays an important role for the inhibition of metaflammation-related biomarkers. Immunobiology. 2020 Jan;225(1):151874. doi: 10.1016/j.imbio.2019.11.009. Epub 2019 Nov 29.

475. Clausen F,  Behrens HM, Krüger S, Röcken C. Sexual dimorphism in gastric cancer: tumor-associated neutrophils predict patient outcome only for women. J Cancer Res Clin Oncol. 2020 Jan;146(1):53-66. doi: 10.1007/s00432-019-03082-z.

474. Ulase D, Heckl S, Behrens HM, Krüger S, Röcken C. Prognostic significance of tumour budding assessed in gastric carcinoma according to the criteria of the International Tumour Budding Consensus Conference. Histopathology 2020 Feb;76(3):433-446. doi: 10.1111/his.13997


2019

473. Gundlach JP, Günther R, Fickenscher H, Both M, Röcken C, Becker T, Braun F. Lethal thrombosis of the iliac artery caused by Aspergillus fumigatus after liver transplantation. Case report and review of the literature. BMC Surg. 2019 Dec 27;19(1):200. doi: 10.1186/s12893-019-0668-4.

472. Rahn S, Barbosa PD, Möller JL, Ammar N, Demetrowitsch T, Helm O, Wesch D, Sipos B, Röcken C, Schwarz K, Schäfer H, Sebens S. Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells. Cancers (Basel). 2019 Dec 21;12(1). pii: E42. doi: 10.3390/cancers12010042.

471. Freiin Grote A, Halske C, Behrens HM, Krüger S, Wilhelm F, Egberts JH, Röcken C. Expression of LGR5, FZD7, TROY and MIST1 in perioperatively treated gastric carcinomas and correlation with therapy response. Dis Markers. 2019 Nov 19;2019:8154926. doi: 10.1155/2019/8154926

470. Moehler M, Al-Batran SE, Andus T, Arends J, Arnold D, Baretton G, Bornschein J, Budach W, Daum S, Dietrich C, Ebert M, Fischbach W, Flentje M, Gockel I, Grenacher L, Haier J, Höcht S, Jakobs R, Jenssen C, Kade B, Kanzler S, Langhorst J, Link H, Lordick F, Lorenz D, Lorenzen S, Lutz M, Messmann H, Meyer HJ, Mönig S, Ott K, Quante M, Röcken C, Schlattmann P, Schmiegel WH, Schreyer A, Tannapfel A, Thuss-Patience P, Weimann A, Unverzagt S. S3-Leitlinie Magenkarzinom – Diagnostik und Therapie der Adenokarzinome des Magens und des ösophagogastralen Übergangs – Langversion 2.0 – August 2019. AWMF-Registernummer: 032/009OL. Z Gastroenterol. 2019 Dec;57(12):1517-1632. doi: 10.1055/a-1018-2516.

469. Röcken C. Definiton und Klassifikation der Amyloidosen. Pathogenese der Amyloidosen. In: Sommer C, Birklein F, Hund E (Hrsg.). Hereditäre Amyloidneuropathien. UNI-MED, Bremen, 2019; S. 13-2

468. Segovia-Miranda F, Morales-Navarrete H, Kücken M, Moser V, Seifert S, Repnik U, Rost F, Brosch M, Hendricks A, Hinz S, Röcken C, Lütjohann D, Kalaidzidis Y, Schafmayer C, Brusch L, Hampe J, Zerial M. Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression. Nat Med. 2019 Dec;25(12):1885-1893. doi: 10.1038/s41591-019-0660-7

467. Tober JM, Halske C,  Behrens HM, Krüger S, Röcken C. Intratumoral heterogeneity and loss of ARID1A expression in gastric cancer correlates with increased PD-L1 expression in Western patients. Hum Pathol. 2019 Nov 6;94:98-109. doi: 10.1016/j.humpath.2019.09.016

466. Röcken C.Seltene Erkrankungen. Pathologe. 2019 Nov;40(6):582. doi: 10.1007/s00292-019-00686-7

465. Li T, Li B, Sara A, Ay C, Leung WY, Zhang Y, Dong Y, Liang Q, Zhang X, Weidner P, Gutting T, Behrens HM, Röcken C, Sung JJ, Ebert MP, Yu J, Burgermeister E. Docking protein-1 promotes inflammatory macrophage signaling in gastric cancer. Oncoimmunology. 2019 Aug 21;8(11):e1649961. doi:10.1080/2162402X.2019.1649961

464. Röcken C (2019) Jejunum und Ileum. In: Höfler G, Kreipe H, Moch H (eds.) Lehrbuch Pathologie, 6. Auflage Urban & Fischer Verlag/Elsevier GmbH, München, pp. 581-598

463. Röcken C (2019) Appendix. In: Höfler G, Kreipe H, Moch H (eds.) Lehrbuch Pathologie, 6. Auflage Urban & Fischer Verlag/Elsevier GmbH, München, pp.599-603

462. Spinas GA, Röcken C (2019) Stoffwechselerkrankungen. In: Höfler G, Kreipe H, Moch H (eds.) Lehrbuch Pathologie, 6. Auflage Urban & Fischer Verlag/Elsevier GmbH, München, pp. 929-948

461. Just C, Knief J, Lazar-Karsten P, Petrova E, Hummel R, Röcken C, Wellner U, Thorns C. MicroRNAs as potential biomarkers for chemoresistance in adenocarcinomas of the esophagogastric junction. J Oncol. 2019 Jul 29;2019:4903152. doi: 10.1155/2019/4903152

460. Röcken C. Molekularpathologie zur Prädiktion von Prognose und Therapie bei Tumorerkrankungen. Onkologe. 2019; 25 (Suppl 1): S54–S60; doi.org/10.1007/s00761-019-0640-z

459. Dottermusch M, Krüger S, Behrens HM, Halske C, Röcken C. Expression of the potential therapeutic target claudin-18.2 is frequently decreased in gastric cancer: results from a large Caucasian cohort study. Virchows Arch. 2019 Nov;475(5):563-571. doi: 10.1007/s00428-019-02624-7

458. Ghilardi G, Stussi G, Mazzucchelli L, Röcken C, Rossi D, Gerber B. Venetoclax plus daratumumab induce hematological CR and organ response in an AL amyloidosis patient with t(11;14). Amyloid. 2019; 26(3):173-174. doi: 10.1080/13506129.2019.1615428

457. Heilmann T, Vondung F, Borzikowsky C, Szymczak S, Krüger S, Alkatout I, Wenners A, Bauer M, Klapper W, Röcken C, Maass N, von Karstedt S, Schem C, Trauzold A. Heterogeneous intracellular TRAIL-receptor distribution predicts poor outcome in breast cancer patients. J Mol Med (Berl). 2019; 97(8):1155-1167. doi: 10.1007/s00109-019-01805-w.

456. Fritscher-Ravens A, Pflaum  T, Mösinger M, Ruchay Z, Röcken C, Milla PJ, Das M, Böttner M, Wedel T, Schuppan D. Many patients with irritable bowel syndrome have atypical food allergies not associated with immunoglobulin E. Gastroenterology. 2019 Jul;157(1):109-118.e5. doi: 10.1053/j.gastro.2019.03.046.

455. Schäffler HP, Li W, Helm O, Krüger S, Böger C, Peters F, Röcken C, Sebens S, Lucius R, Becker-Pauly C, Arnold P. The cancer associated meprin β variant p.G32R provides an additional activation site and promotes cancer cell invasion. J Cell Sci. 2019 May 31;132(11). pii: jcs220665. doi: 10.1242/jcs.220665.

454. Heckl SM, Wiesener V, Behrens HM, Ulase D, Krüger S, Röcken C. The expression of the insulin receptor in gastric cancer correlates with the HER2-status and may have putative therapeutic implications. Gastric Cancer. 2019 Nov;22(6):1130-1142. doi: 10.1007/s10120-019-00964-6.

453. Németh CG, Röcken C, Siebert R, Wiltfang J, Ammerpohl O, Gassling V. Recurrent chromosomal and epigenetic alterations in oral squamous cell carcinoma and its putative premalignant condition oral lichen planus. PLoS One. 2019 Apr 9;14(4):e0215055. doi: 10.1371/journal.pone.0215055

452. Aus dem Siepen F, Hein S, Prestel S, Baumgärtner C, Schönland S, Hegenbart U, Röcken C, Katus HA, Kristen AV. Carpal tunnel syndrome and spinal canal stenosis: harbingers of transthyretin amyloid cardiomyopathy? Clin Res Cardiol. 2019 Dec;108(12):1324-1330. doi: 10.1007/s00392-019-01467-1.

451. Lieb W, Jacobs G, Wolf A, Richter G, Gaede KI, Schwarz J, Arnold N, Böhm R, Buyx A, Cascorbi I, Franke A, Glinicke C, Held-Feindt J, Junker R, Kalthoff H, Kramer HH, Leypoldt F, Maass N, Maetzler W, May S, Mehdorn HM, Röcken C, Schafmayer C, Schrappe M, Schreiber S, Sebens S, Stephani U, Synowitz M, Weimer J, Zabel P, Nöthlings U, Röder C, Krawczak M. Linking pre-existing biorepositories for medical research: The PopGen 2.0 Network. J Community Genet. 2019 Mar 29. doi: 10.1007/s12687-019-00417-8.

450. Rahn S, Krüger S, Mennrich R, Göbel L, Wesch D, Oberg HH, Vogel I, Ebsen M, Röcken C, Helm O, Sebens S. POLE score: a comprehensive profiling of programmed death 1 ligand 1 expression in pancreatic ductal adenocarcinoma. Oncotarget. 2019 Feb 22;10(16):1572-1588. doi: 10.18632/oncotarget.26705.

449. Lutz MP, Zalcberg J, Ducreux M, Adenis A, Allum W, Aust D, Carneiro F, Grabsch HI; Laurent-Puig P, Lordick F, Moehler M, Moenig S, Obermannova R, Piessen G, Riddell A, Röcken C, Roviello F, Schneider PM, Seewald S, Smyth E, Van Cutsem E, Verheij M, Wagner DA, Otto F. 4th St. Gallen EORTC Gastrointestinal Cancer Conference:  Controversial Issues in the Multimodal Primary Treatment of Gastric, Junctional and Oesophageal Adenocarcinoma. Eur J Cancer. 2019 Mar 14;112:1-8. doi: 10.1016/j.ejca.2019.01.106.

448. Krause C, Schawitzke A, Grunow R, Jacob D, Röcken C, Egberts JH. Seltene Differenzialdiagnose PET-positiver pulmonaler Raumforderungen. Chirurg. 2019 Jun;90(6):493-495. doi: 10.1007/s00104-019-0803-x.

447. Stuhlmann-Laiesz C, Schönland SO, Hegenbart U, Oschlies I, Baumgart JV, Krüger S, Röcken C. AL amyloidosis with a localized B-cell neoplasia. Virchows Arch. 2019 Mar;474(3):353-363. doi: 10.1007/s00428-019-02527-7.

446. Rahn S, Krüger S, Röcken C, Helm O, Sebens S. Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma. Gut. 2019 Jan;68(1):179-180. doi: 10.1136/gutjnl-2017-315843. Epub 2018 Feb 7.

445. Gärtner F, Krüger S, Röder C, Trauzold A, Röcken C, Kalthoff H. The expression of death receptor systems TRAIL-R1/-R2/-R4, CD95 and TNF-R1 and their cognate ligands in pancreatic ductal adenocarcinoma. Histol Histopathol. 2019 May;34(5):491-501. doi: 10.14670/HH-18-054

444. Kha ML, Hesse L, Deisinger F, Sipos B, Röcken C, Arlt A, Sebens S, Helm O, Schäfer H. The antioxidant transcription factor Nrf2 modulates the stress response and phenotype of malignant as well as premalignant pancreatic ductal epithelial cells by inducing expression of the ATF3 splicing variant ΔZip2. Oncogene. 2019 Feb;38(9):1461-1476. doi: 10.1038/s41388-018-0518-3.

443. Aden K, Bartsch K, Dahl J, Reijns MAM, Esser D, Sheibani-Tezerji R, Sinha A, Wottawa F, Ito G, Mishra N, Knittler K, Burkholder A, Welz L, van Es J, Tran F, Lipinski S, Kakavand N, Boeger C, Lucius R, von Schoenfels W, Schafmayer C, Lenk L, Chalaris A, Clevers H, Röcken C, Kaleta C, Rose-John S, Schreiber S, Kunkel T, Rabe B, Rosenstiel P. Epithelial RNase H2 maintains genome integrity and prevents intestinal tumorigenesis in mice. Gastroenterology. 2019 Jan;156(1):145-159.e19. doi: 10.1053/j.gastro.2018.09.047. Epub 2018 Sep 28

442. Quabius ES, Loehr J, Haaser D, Günther V, Maass N, Röcken C, Mathiak M, Alkatout I, Hoffmann M. Smoking-Induced SLPI Expression Hinders HPV Infections Also in Squamous Cell Carcinomas of the Vulva. Transl Oncol. 2019 Jan;12(1):36-42. doi: 10.1016/j.tranon.2018.09.004. Epub 2018 Sep 26

2018

441. Heckl SM, Pellinghaus M, Krüger S, Bosselmann C, Wilhelm F, Behrens HM, Schreiber S, Röcken C. Epithelial insulin receptor expression – prognostic relevance in colorectal cancer. Oncotarget. 2018; 9:37497-37508

440. Hahn K, Urban P, Meliß RR, Axmann HD, Siebert F, Röcken C. Karpaltunnelsyndrom und ATTR-Amyloidose. Handchir Mikrochir Plast Chir. 2018 Sep;50(5):329-334. doi: 10.1055/a-0747-6096.

439. Röcken C. Das Amyloid Register Kiel - eine Zwischenbilanz. Pathologe. 2018 Dec;39(Suppl 2):301-305

438. Röcken C. Eröffnungsrede zur 102. Jahrestagung der DGP. Pathologe. 2018 Dec;39(Suppl 2):175-176

437. Brosch M, Kattler K, Herrmann A, von Schönfels W, Nordström K, Seehofer D, Damm G, Becker T, Zeissig S, Nehring S, Reichel F, Moser V, Thangapandi RV, Stickel F, Baretton G, Röcken C, Muders M, Matz-Soja M, Krawczak M, Gasparoni G, Hartmann H, Dahl A, Schafmayer C, Walter J, Hampe J. Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control. Nat Commun. 2018 Oct 8;9(1):4150. doi: 10.1038/s41467-018-06611-5.

436. von Schönfels W, Beckmann JH, Ahrens M, Hendricks A, Röcken C, Hampe J, Becker T, Schafmayer C. Histological improvement of NAFLD in patients with obesity after bariatric surgery based on standardized NAS. Surg Obes Relat Dis. 2018 Jul 24. pii: S1550-7289(18)30413-1.

435. Hund E, Kristen A, Auer-Grumbach M, Geber C, Birklein F, Schulte-Mattler W, Sommer C, Schmidt H, Röcken C. Transthyretin-Amyloidose (ATTR-Amyloidose): Empfehlungen zum Management in Deutschland und Österreich Empfehlungen der Deutschen Gesellschaft für Amyloiderkrankungen e.V. Aktuelle Neurologie 2018; 45(08): 605 - 616.

434. Röcken C. (2018) Endokrinium. In: Kirchner T, Müller-Hermelink K, Roessner A (eds) Kurzlehrbuch Pathologie. Kapitel 18, 13. Aufl. Urban & Fischer, München, pp elektronisch: www.mediscript-online.de. ISBN 9783437433085

433. Baumgart JV, Stuhlmann-Laeisz C, Hegenbart U, Nattenmüller J, Schönland S, Krüger S, Behrens HM, Röcken C. Local vs. systemic pulmonary amyloidosis - impact on diagnostics and clinical management. Virchows Archiv 2018 Nov;473(5):627-637


432. Gundlach JP, Hauser C, Schlegel FM, Böger C, Röder C, Röcken C, Becker T, Egberts JH, Kalthoff H, Trauzold A. Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC. BMC Cancer. 2018 Jul 31;18(1):777. doi: 10.1186/s12885-018-4688-8.

431. Heits N, Brosch M, Herrmann A, Behrens R, Röcken C, Schrem H, Kaltenborn A, Klempnauer J, Kreipe HH, Reichert B, Lenschow C, Wilms C, Vogel T, Wolters H, Wardelmann E, Seehofer D, Buch S, Zeissig S, Pannach S, Raschzok N, Anagnostopoulos I, von Schoenfels W, Hinz S, Teufel A, Evert M, Franke A, Becker T, Braun1 F, Hampe J, Schafmayer C. Evolutionary distance predicts recurrence after liver transplantation in mulitfocal hepatocellular carcinoma. Transplantation. 2018 Oct;102(10):e424-e430. doi: 10.1097/TP.0000000000002356.

430. Aselmann H, Kersebaum JN, Bernsmeier A, Möller T, Beckmann JH, Egberts JH, Schafmayer V, Röcken C, Becker T. Robotic assisted total mesorectal excision (TME) for rectal cancer results in a significantly higher quality of TME specimen compared to the laparoscopic approach - report of a single center experience. Int J Colorectal Dis. 2018 Nov;33(11):1575-1581. doi: 10.1007/s00384-018-3111-x. Epub 2018 Jul 4.

429. Röcken C. Journal Club - Neues Format in Der Pathologe. Pathologe. 2018 Jul; 39(4):287.

428. Vollmers PL, Mundhenke C, Maass N, Bauerschlag D, Kratzenstein S, Röcken C, Schmidt T. Evaluation of the effects of sensorimotor exercise on physical and psychological parameters in breast cancer patients undergoing neurotoxic chemotherapy. J Cancer Res Clin Oncol. 2018 Sep;144(9):1785-1792. doi: 10.1007/s00432-018-2686-5.

427. Wehkamp U, Stern S, Krüger S, Weichenthal M, Hauschild A, Röcken C, Egberts F. Co-expression of NGF and PD-L1 on tumor associated immune cells in the microenvironment of Merkel cell carcinoma. J Cancer Res Clin Oncol. 2018 May 9. doi: 10.1007/s00432-018-2657-x. [Epub ahead of print]

426. Röcken C. Magenkarzinom: Histopathologie und Tumorbiologie. In: Messmann H, Tannapfel A, Werner J (eds.) Gastrointestinale Onkologie. Georg Thieme Verlag KG, Stuttgart. ISBN: 9783131767615


425. Röcken C. Digitale Medizin in 2018. Pathologe. 2018 May; 39(3):215.

424. Legler K, Hauser C, Egberts JH, Willms A, Henerweer C, Boretius S, Röcken C, Glüer CC, Becker T, Kluge M, Hill O, Gieffers C, Fricke H, Kalthoff H, Lemke J, Trauszold A. The novel TRAIL-Receptor agonist APG350 exerts superior therapeutic activity in pancreatic cancer cells. Cell Death Dis. 2018 Apr 18;9(5):445

423. Polom K, Böger C, Smyth E, Marrelli D, Behrens HM, Marano L, Becker T, Lordick F, Röcken C, Roviello F. Synchronous metastatic gastric cancer- molecular background and clinical implications with special attention to mismatch repair deficiency. Eur J Surg Oncol. 2018 May; 44(5):626-631.

422. Niemietz C, Röcken C, Schilling M, Stypman J, Uhlig CE, Schmidt HH. Transthyretin-assoziierte familiäre Amyloidpolyneuropathie. Wann es wichtig ist, daran zu denken. Dtsch Med Wochenschr. 2018 Mar;143(6):427-430. doi: 10.1055/s-0043-123681

421. Blank N, Hegenbart U, Dietrich S, Brune M, Beimler J, Röcken C, Müller-Tidow C, Lorenz HM, Schönland S. Obesity is a significant susceptibility factor for idiopathic AA amyloidosis. Amyloid. 2018 Mar; 25(1):37-45. doi: 10.1080/13506129.2018.1429391.

420. Schmidt T, Jonat W, Wesch D, Oberg HH, Adam-Klages S, Keller L, Röcken C, Mundhenke C. Influence of physical activity on the immune system in breast cancer patients during chemotherapy. J Cancer Res Clin Oncol. 2018 Mar; 144(3):579-586.

419. Siepen FAD, Bauer R, Voss A, Hein S, Aurich M, Riffel J, Mereles D, Röcken C, Buss SJ, Katus HA, Kristen AV. Predictors of survival stratification in patients with wild-type cardiac amyloidosis. Clin Res Cardiol. 2018 Feb;107(2):158-169.

418. Hendricks C, Fernández Figueras MT, Liersch J, Martin-Urdà MT, López D, Brochhausen C, Röcken C, Schaller J. Cutaneous light chain deposition disease: A report of two cases and review of the literature. Am J Dermatopathol. 2018; 40(5):337-341.

417. Diehl K, Dinges LA, Helm O, Ammar N, Plundrich D, Arlt A, Röcken C, Sebens S, Schäfer H. Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells. Oncogene. 2018;37(1):39-51.

416. Heß K, Purrucker J, Hegenbart U, Brokinkel B, Keyvani K, Monoranu CM, Löhr M, Reifenberger G, Bendix CM, Kalla J, Schick U, Klapper W, Röcken C, Hasselblatt M, Paulus W. Cerebral amyloidoma is characterized by B-cell clonality and a stable clinical course. Brain Pathol. 2018 Mar;28(2):234-239.


2017

415. Lenk L, Peinb M, Will O, Gomez B, Viol F, Hauser C, Egberts JH, Gundlach JP, Helm O, Tiwari S, Weiskirchen R, Rose-John S, Röcken C, Mikulits W, Wenzel P, Schneider G, Saur D, Schäfer H, Sebens S. The hepatic microenvironment determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma. Oncoimmunol. 2017;7(1):e1368603.

414. Kollikowski AM, Kahles F, Kintsler S, Hamada S, Reith S, Knüchel R, Röcken C, Mottaghy EM, Marx N, Burgmaier M. In vivo quantification of amyloid burden in TTR-related cardiac amyloidosis. Intractable Rare Dis Res. 2017;6(4):291-294

413. Quabius ES, Merz I, Görögh T, Hedderich J, Haag J, Röcken C, Ambrosch P, Hoffmann M. miRNA-expression in tonsillar squamous cell carcinomas in relation to HPV infection and expression of the antileukoproteinase SLPI. Papillomavirus Res. 2017;4:26-34.

412. Burgermeister E, Höde P, Betge J, Tänzer M, Mossner M, Nowak D, Magdeburg J, Rückert F, Sticht C, Breitkopf-Heinlein K, Schulte N, Härtel N, Post S, Ingold-Heppner B, Behrens HM, Röcken C, Ebert M. Epigenetic silencing of tumor suppressor candidate 3 confers adverse prognosis in early colorectal cancer. Oncotarget. 2017;8:84714-84728

411. Ghadimi D, Frahm SO,  Ebsen M, Röcken C, de Vrese M, Heller KJ, Bockelmann W. Calcium propionate alleviates DSS-induced colitis and influences lipid profile, Interferon gamma, peptidoglycan recognition protein 3 and calprotectin in one-year-old female and male C57BL/6 mice. Scientific Journal of Immunology & Immunotherapy. 2017;2(1): 007-010.

410. Röcken C. Industrie 4.0 in der Pathologie. Pathologe. 2017;38(6):489.

409. Winter M, Tholey A, Kristen A, Röcken C. MALDI Mass spectrometry imaging: a novel tool for the identification and classification of amyloidosis. Proteomics. 2017;17(22). doi: 10.1002/pmic.201700236.

408. Schirmacher P, Tannapfel A, Dietel M, Röcken C, Büttner R, Chen Y, Aigner T, Haas C, Knolle J, Kellner U, Streckert HJ, Reineke-Plaas T, Meier T, Sterlacci W, Bittmann I, Streubel A, Schildgen V, Steinbach-Buchert AK, Krenzer S, Baretton GB. RAS Registry: Molecular pathological analysis of RAS mutations in mCRC. Virchows Archiv. 2017; 471: S33-S34.

407. Romagnoli  G, Wiedermann M, Hübner F, Wenners A, Mathiak M, Röcken C, Maass N, Wolfram Klapper, Alkatout I. Morphological evaluation of tumor-infiltrating lymphocytes (TILs) to investigate invasive breast cancer immunogenicity, reveal lymphocytic networks and help relapse prediction: a retrospective study. Int J Mol Sci. 2017;18(9). pii: E1936.

406. Wehkamp U, Stern S, Krüger S, Röcken C, Hauschild A, Egberts F. TrkA expression on Merkel cell carcinoma tumor cells. JAMA Dermatol. 2017;153(11):1166-1169.

405. Esser D, Holze N, Haag J, Schreiber S, Krüger S, Warneke V, Rosenstiel P, Röcken C. Interpreting whole genome and exome sequencing data of individual gastric cancer samples. BMC Genomics. 2017 Jul 6;18(1):517.

404. Kollmer J, Sahm F, Hegenbart U, Purrucker JC, Kimmich C, Schönland SO, Jund E, Heiland S, Hayes JM, Kristen AV, Röcken C, Pham M, Benszus M, Weiler M. Sural nerve injury in familial amyloid polyneuropathy - MR neurography vs clinicopathologic tools. Neurology. 2017;89(5):475-484.

403. Gödecke VA, Röcken C, Steinmüller-Magin L, Blessing J, Nadrowitz F, Fleig S, Haller H, Wagner AD. Mixed leukocyte cell–derived chemotaxin 2 and amyloid a renal amyloidosis in a Kazakh-German patient. Clin Kidney J 2017;10(2): 266–268.

402. Böger C, Behrens HM, Krüger S, Röcken C. The novel negative checkpoint regulator VISTA is expressed in gastric carcinoma and correlated with PD-L1/PD-1: A future perspective for a combined gastric cancer therapy? Oncoimmunol. 2017;6 (4): e1293215.

401. Böger C, Krüger S, Behrens HM, Bock S, Haag J, Kalthoff H, Röcken C. Epstein-Barr virus-associated gastric cancer reveals intratumoral heterogeneity of PIK3CA mutations. Ann Oncol. 2017;28(5):1005-1014.

400. Schmidt T, Schwarz M, van Mackelenbergh M, Jonat W, Weisser B, Röcken C, Mundhenke C. Feasibility study to evaluate compliance of physical activity over a long time period and its influence on the total activity score, glucose metabolism and physical and psychological parameters following breast cancer. Mol Clin Oncol. 2017;5:397-402.

399. Guttmann S, Röcken C, Schmidt M, Grünewald I, Zibert A, Stypmann J, Schilling M, Schmidt H. De novo hereditary (familial) amyloid polyneuropathy (FAP) in a FAP liver recipient. Amyloid. 2017;24(S1): 126–127.

398. Hahn K, Nilsson PR, Hammarström P, Urban P, Meliss RR, Behrens HM, Krüger S, Röcken C. Establishing and validating the fluorescent amyloid ligand h-FTAA (heptamer formyl thiophene acetic acid) to identify transthyretin amyloid deposits in carpal tunnel syndrome. Amyloid. 2017;24(2):78-86.

397. Röcken C, Baretton GB, Kreipe HH, Kirchner T. Universitäre Pathologie in Deutschland – eine Standortbestimmung. Pathologe. 2017;39 (4):324-330.

396. Saboor Maleki S, Röcken C. Chromosomal instability in gastric cancer biology. Neoplasia. 2017;19(5):412-420.

395. Harms D, Röcken C. Ivo Leuschner: 14/06/1959-29/01/2017. Pathologe. 2017;38(Suppl 2):254

394. Röcken C. Histopathologische und molekulare Subklassen des Magenkarzinoms. J Onkologie. 2017;2:124-129.

393. Lordick F, Al-Batran S, Hofheinz R, Lorenzen S, Thuss-Patience P, Baretton G, Dietel M, Gaiser T, Kirchner T, Kreipe HH, Quaas A, Röcken C, Rüschoff J, Tannapfel A. HER2 testing in gastric cancer - results of a German expert meeting. J Cancer Res Clin Oncol. 2017;143(5):835-841.

392. Alkatout IF, Hübner F, Wenners A, Hedderich J, Wiedermann M, Sanchez C, Röcken C, Mathiak M, Maas N, Klapper W. In situ localization of tumor cells associated with the epithelial-mesenchymal transition marker Snail and the prognostic impact of lymphocytes in the tumor microenvironment in invasive ductal breast cancer. Exp Mol Pathol. 2017;102(2):268-275.

391. Wilhelm F, Simon E, Böger C, Behrens HM, Krüger S, Röcken C. Novel insights into gastric cancer: Methylation of R-spondins and regulation of LGR5 by SP1. Mol Cancer Res. 2017;15(6):776-785.

390. Röcken C. Molecular classification of gastric cancer. Expert Rev Mol Diagn. 2017;17(3):293-301.

389. Schmidt T, Berner J, Jonat W, Weisser B, Röcken C, van Mackelenbergh M, Mundhenke C. Influence of arm crank ergometry on development of lymphoedema in breast cancer patients after axillary dissection: a trandomized controlled trial.
J Rehabil Med. 2017;49(1):78-83.

388. Röcken C. Tumoren und Tumorvorstufen des Magens. Pathologe. 2017 Mar;38(2):75-86.

387. Mathiak M, Warneke VS, Behrens HM, Haag J, Böger C, Krüger S, Röcken C. Clinico-pathological characteristics of microsatellite instable gastric carcinomas revisited - Urgent need for standardization. Appl Immunohistochem Mol Morphol. 2017;25(1):12-24.

386. Ammerpohl O, Hattermann K, Held-Feindt J, Röcken C, Schäfer H, Schem C, Schewe D, Schulenburg H, Sebens S, Synowitz M, Tiwari S, Traulsen A, Trauzold A, Valerius T, Wech D. Dormancy: An Evolutionary Key Phenomenon in Cancer Development. In: Ujvari B, Roche B, Thomas F (Hrsg.) Ecology and Evolution of Cancer. Academic Press. London. UK. 2017: S. 235-242

2016

385. Kristen AV, Brokbals E, Siepen F, Bauer R, Hein S, Aurich M, Riffel J, Behrens HM, Krüger S, Schirmacher P, Katus HA, Röcken C. Should Histologic Determination of Amyloid Load Determine Management Decisions in Light-Chain Amyloidosis? J Am Coll Cardiol. 2016;68(22):2493-94.

384. Röcken C. Histopathologie des Magen- und Kardiakarzinoms. In: Kreis ME,  Seeliger H (Hrsg.). Moderne Chirurgie des Magen- und Kardiakarzinoms. Springer Medizin, Heidelberg, 2017; ISBN 978-3-662-53188-4

383. Röcken C. Companion Diagnostics: Ein neues Erfordernis klinischer Forschung in der Onkologie? Forum. 31(5), 406-411.

382. Kruse ML, Friedrich M, Arlt A, Röcken C, Egberts JH, Sebens S, Schäfer H. Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protection in Human Colonocytes.Inflamm Bowel Dis. 2016;22(11):2593-2606.

381. Lordick F, Al-Batran S, Hofheinz R, Lorenzen S, Thuss-Patience P, Baretton G, Dietel M, Gaiser T, Kirchner T, Kreipe HH, Quaas A, Röcken C, Rüschoff J, Tannapfel A. HER2-Testung beim Magenkarzinom  – Ergebnisse eines deutschen Expertentreffens. Z Gastroenterol. 2016;54(8):791-6.

380. Fischbach W, Malfertheiner P, Lynen Jansen P, Bolten W, Bornschein J, Buderus S, Glocker E, Hoffmann JC, Koletzko S, Labenz J, Mayerle J, Miehlke S, Mössner J, Peitz U, Prinz C, Selgrad M, Suerbaum S, Venerito M, Vieth M, Berger T, Ebert M, Eck M, Flieger D, Gross M, Jung M, Kellner H, Koop H, Layer P, Leodolter A, Madisch A, Meining A, Möhler M, Mönnikes H, Nickenig G, Rad R, Röcken C, Rosien U, Schepp W, Scherübl H, Siegmund B, Storr M, Vabanova M, Wagner S. S2k-Leitlinie Helicobacter pylori und gastroduodenale Ulkuskrankheit. Z Gastroenterol. 2016;54(4):327-63.

379. Friedrich T, Söhn M, Gutting T, Janssen KP, Behrens HM, Röcken C, Ebert MP, Burgermeister E. Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer. EBioMedicine. 2016;8:159-172.

378. Oberg HH, Grabe-Griebenow E, Adam-Klages S, Jerg E, Peipp M, Kellner C, Petrick D, Gonnermann D, Freitag-Wolf  S, Röcken C, Sebens T, Vogel I, Becker T, Ebsen M, Kabelitz D, Wesch D, Sebens S. Monitoring and functional characterization of the lymphocytic compartment in pancreatic ductal adenocarcinoma patients. Pancreatology. 2016;16(6):1069-1079.

377. Wilhelm F, Böger C, Krüger S, Behrens HM, Röcken C. Troy is expressed in human stomach mucosa and a novel putative prognostic marker of intestinal type gastric cancer. Oncotarget. 2016;8(31):50557-50569.

376. Weidner P, Söhn M, Gutting T, Friedrich T, Gaiser T, Magdeburg J, Kienle P, Ruh H, Hopf C, Behrens HM, Röcken C, Hanoch T, Seger R, Ebert MP, Burgermeister E. Myotubularin-related protein 7 inhibits insulin-signaling in colorectal cancer. Oncotarget. 2016;7(31):50490-50506.

375. Baretton G, Dietel M, Gaiser T, Kirchner T, Kreipe HH, Quaas A, Röcken C, Rüschoff J, Tannapfel A, Lordick F, Al-Batran S, Hofheinz R, Lorenzen S, Moehler M, Thuss-Patience P. HER2-Testung beim Magenkarzinom  – Ergebnisse eines deutschen Expertentreffens. Pathologe. 2016;37(4):361-6.

374. Kristen AV, Brokbals E, Siepen F, Bauer R, Hein S, Aurich M, Riffel J, Behrens HM, Krüger S, Schirmacher P, Katus HA, Röcken C. Cardiac amyloid load: a prognostic and predictive biomarker at diagnosis prior to chemotherapy in AL amyloidosis. J Am Coll Cardiol. 2016;68(1):13-24.

373. Andradas C, Blasco-Benito S, Castillo-Lluva S, Dillenburg-Pilla P, Diez-Alarcia R, Juanes-García A, García-Taboada E, Hernando-Llorente R, Soriano J, Hamann S, Wenners A, Alkatout I, Klapper W, Röcken C, Bauer M, Arnold N, Quintanilla M, Megías D, Vicente-Manzanares M, Urigüen L, Gutkind JS, Guzmán M, Pérez-Gómez E, Sánchez C. Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer. Oncotarget. 2016;7(30):47565-47575.

372. Röcken C. Definiton und Klassifikation der Amyloidosen. Pathogenese der Amyloidosen. In: Sommer C. (Hrsg.). Hereditäre Amyloidneuropathien. UNI-MED, Bremen, 2016; S. 11-17 & S. 39-43

371. Schmidt T, Hermes A, Voigt C, Schade J, Röcken C, Hübner J, Naumann C. Implementierung und Evaluation sporttherapeutischer Trainingsmethoden nach Prostataektomie. Forum. 2016; 31:230–231

370. Baldus C, Röcken. Tumorheterogenität. Forum. 2016;31:212-215.

369. Balke L, Both M, Winkler C, Röcken C, Koch K, Bewig B. Scintigraphy misleading to the diagnosis of chronic thromboembolic disease in a patient with pulmonary veno-occlusive disease. Circulation. 2016;133:1627-1628

368. Lisenko K, Schönland S, Jauch A, Andrulis M, Röcken C, Ho AD, Goldschmidt H, Hegenbart U, Hundemer M. Flow cytometry-based characterization of underlying clonal B and plasma cells in patients with light chain amyloidosis. Cancer Med. 2016;5(7):1464-72.

367. Heits N, Finsterbusch J, Röcken C, Schaefer P, Guenther R, Aselmann H, Egberts JH, Beckmann J, Schafmayer C, Reichert B, Bernsmeier A, Hampe J, Becker T, Braun F. Is there a benefit from rescue-allocated organs for HCC-patients staged outside Milan Criteria? J Liver: Dis Transplant. 2016;5:1.

366. Peuker K, Muff S, Bosse E, Zeissig Y, Ulbricht A, Kaser A, Arlt A, Hampe1 J, Schafmayer C, Egberts JH, Becker T, Röcken C, Schreiber S, Blumberg RS, Zeissig S. Epithelial calcineurin in the control of microbiota-dependent intestinal tumor development. Nat Med. 2016; 22(5):506-15.

365. Morgenthal S, Bayer R, Schneider E, Zachäus M, Röcken C, Dreßler J, Ondruschka B. Nodular pulmonary amyloidosis with spontaneous fatal blood aspiration. Forensic Sci Int. 2016;262:e1-4.

364. Böger C, Behrens HM, Mathiak M, Krüger S, Kalthoff H, Röcken C. PD-L1 is an independent prognostic predictor in gastric cancer of Western patients. Oncotarget. 2016;7(17):24269-83.

363. Sjölander D, Röcken C, Westermark P, Westermark GT, Nilsson KPR, Hammarström P. Establishing the fluorescent amyloid ligand h-FTAA for studying human tissues with systemic and localized amyloid. Amyloid. 2016;23(2):98-108.

362. Wong YL, Lautenschläger I, Zitta K, Schildhauer C, Parczany K, Röcken C, Steinfath M, Weiler N, Albrecht M. Adverse effects of hydroxyethyl starch (HES 130/0.4) on intestinal barrier integrity and metabolic function are abrogated by supplementation with albumin. J Transl Med. 2016;14(1):60.

361. Genrich G, Kruppa M, Lenk L, Helm O, Broich A, Freitag-Wolf S, Röcken C, Sipos B, Schäfer H, Sebens S. The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of protumorigenic functions of TGF-β1. BMC Cancer. 2016;16(1):155.

360. Freudenthaler S, Hegenbart U, Schönland S, Behrens HM, Krüger S, Röcken C. Amyloid in biopsies of the gastrointestinal tract - a retrospective observational study on 542 patients. Virchows Arch. 2016;468(5):569-77.

359. Köhler WM, Naumann CM, Hamann M, Bothe K, Röcken C, Jünemann K, Osmonov. Muzinöses Adenokarzinom des Urachus – Ein Fallbericht. Aktuelle Urol. 2016;47(2):141-3.

358. Böger C, Behrens HM, Röcken C. Ki67 - an unsuitable marker of gastric cancer prognosis unmasks intratumoral heterogeneity. J Surg Oncol. 2016 Jan;113(1):46-5

357. Böger C, Haag J, Egberts JH, Röcken C. Complex APC germline mutation associated metaplasia and intraepithelial neoplasia (CAM-IEN) of the gallbladder. Path Res Pract. Pathol Res Pract. 2016;212(1):54-58.

356. Khatib R, Göbel H, Kurschat C, Röcken C, Cursiefen C, Steven P, Heindl LM.
Therapierefraktäre follikuläre Konjunktivitis. Ophthalmologe. 2016 Jul;113(7):612-4.

355. Egberts F, Bohne AS, Krüger S, Hedderich J, Rompel R, Haag J, Röcken C, Hauschild A. Varying mutational alterations in multiple primary melanomas. J Mol Diagn. 2016;18(1):75-83.

354. Röcken C. Quality assurance in clinical trials - the role of pathology. Virchows Arch. 2016 Jan;468(1):83-92.

353. Röcken C, Behrens HM, Böger C, Krüger S. Clinico-pathological characteristics of RHOA mutations in a Central European gastric cancer cohort. J Clin Pathol. 2016;69 (1):70-5.

352. Metzger ML, Behrens HM, Böger C, Haag J, Krüger S, Röcken C. MET in gastric cancer - discarding a 10% cutoff rule. Histopathology. 2016;68(2):241-53


2015

351. Schmidt T, Weisser B, Dürkop J, Jonat W, van Mackelenbergh M, Röcken C, Mundhenke C. Comparing endurance and resistance training with standard care during chemotherapy for patients with primary breast cancer. Anticancer Res. 2015;35 (10):5623-5630.

350. Röcken C, Rüschoff J. Identifikation therapeutischer Zielstrukturen: HER2 und neue Targets. In: Lordick F (Hrsg.). Identifikation therapeutischer Zielstrukturen: HER2 und neue Targets. UNI-MED, Bremen, 2015; S. 34-43

349. Goebel L, Grage-Griebenow E, Gorys A, Helm O, Genrich G, Lenk L, Wesch D, Ungefroren H, Freitag-Wolf S, Sipos B, Röcken C, Schäfer H, Sebens S. CD4+ T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4+ T cells in pancreatic cancer development. Oncoimmunology. 2015 Jan 22;4(4):e1000083. eCollection 2015 Apr.

348. Winter M, Tholey A, Krüger S, Schmidt H, Röcken C. MALDI-mass spectrometry imaging identifies vitronectin as common constituent of amyloid deposits. J Histochem Cytochem. 2015 Oct;63(10):772-9.

347. Schmidt T, Armbrecht A, Röcken C, Mundhenke C. Mammakarzinom - verbesserte Heilungschancen durch Sport? TumorDiagn u Ther. 2015;36:209-212

346. Leodolter A, Alonso S, González B, Ebert MP, Vieth M, Röcken C, Wex T, Peitz U, Malfertheiner P, Perucho M. Somatic DNA Hypomethylation in H. pylori-Associated High-Risk Gastritis and Gastric Cancer: Enhanced Somatic Hypomethylation Associates with Advanced Stage Cancer. Clin Transl Gastroenterol. 2015 Apr 30;6:e85. doi: 10.1038/ctg.2015.14.

345. Röcken C. Laudatio auf Prof. Dr. med. Günter Klöppel. Deutscher Krebspreis 2015 – Bereich klinische Forschung. Forum. 2015;30:179.

344. Röcken C. Systemic and localised light chain amyloidosis: two different diseases. Lancet Haematol. 2015;2(6):e227-e228.

343. Pérez-Gómez E, Andradas C, Caffarel MM, Blasco-Benito S, García-Taboada E, Villa-Morales M, Moreno E, Hamann S, Martín-Villar E, Flores JM, Wenners A, Alkatout I, Klapper W, Röcken C, Bronsert P, Stickeler E, Staebler A, Bauer M, Arnold N, Soriano J, Pérez-Martínez M, Megías D, Moreno-Bueno G, Ortega-Gutiérrez S, Artola M, Vázquez-Villa H, Quintanilla M, Fernández-Piqueras J, Canela EI, McCormick PJ, Guzmán M, Sánchez C. Role of cannabinoid receptor CB2 in HER2 pro-oncogenic signaling in breast cancer. J Natl Cancer Inst. 2015 Apr 8;107(6). pii: djv077. doi: 10.1093/jnci/djv077. Print 2015 Jun.

342. von Karstedt S, Conti A, Nobis M, Montinaro A, Hartwig T, Lemke J, Legler K, Annewanter F, Campbell AD, Taraborrelli L, Grosse-Wilde A, Coy JF, El-Bahrawy MA, Bergmann F, Koschny R, Werner J, Ganten TM, Schweiger T, Hoetzenecker K, Kenessey I, Hegedüs B, Bergmann M, Hauser C, Egberts JH, Becker T, Röcken C, Kalthoff H, Trauzold A, Anderson KI, Sansom OJ, Walczak H. Cancer-cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion and metastasis. Cancer Cell. 2015;27(4):561-73.

341. Röcken C. Molekularpathologie. Pathologe. 2015;36(2):125.

340. Heneweer C, Siggelkow M, Helle M, Petzina R, Wulff A, Schaefer J, Berndt R, Rusch R, Wedel T, Klaws G, Mueller-Gerbl M, Röcken C, Jansen O, Lutter G, Cremer J, Gross J. Laser Scoop Desobliteration (LSD) - a novel method for minimal invasive remote recanalization of chronically occluded superficial femoral arteries. J Biomed Opt. 2015 Feb 1;20(2):25005. doi: 10.1117/1.JBO.20.2.025005.

339. Röcken C, Hofstädter F. Qualitätssicherung im Querschnittsfach Pathologie. Forum 2015;30:25-26.

338. Röcken C, Behrens HM. Validating the prognostic and discriminating value of the TNM-classification for gastric cancer - a critical appraisal. Eur J Cancer. 2015;51:577– 586.

337. Kintsler S, Jäkel J, Brandenburg B, Kersten K, Knuechel R, Röcken C. Cardiac amyloidosis in a heart transplant patient - A case report and retrospective analysis of amyloidosis evolution. Intractable Rare Dis Res. 2015;4(1):60-64.

336. Goumas FA, Holmer R, Egberts JH, Gontarewicz A, Heneweer C, Geisen U, Hauser C, Mende MM, Legler K, Röcken C, Becker T, Waetzig GH, Rose-John S, Kalthoff H. Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer. Int J Cancer. 2015;137(5):1035-46.

335. Quabius ES, Görögh T, Fischer GS, Hoffmann AS, Gebhard M, Evert M, Beule A, Maune S, Knecht R, Óvári A, Durisin M, Hoppe F, Röcken C, Hedderich J, Ambrosch P, Hoffmann M. The antileukoprotease secretory leucocyte protease inhibitor (SLPI) and its role in the prevention of HPV-infections in head and neck squamous cell carcinoma. Cancer Lett. 2015;357(1):339-45

334. Quabius ES, Haag J, Kühnel A, Henry H, Hoffmann AS, Görögh T, Hedderich J, Evert M, Beule AG, Maune S, Knecht R, Óvári A, Durisin M, Hoppe F, Tribius S, Röcken C, Ambrosch P, Hoffmann M. Geographical and anatomical influences on human papillomavirus prevalence diversity in head and neck squamous cell carcinoma in Germany. Int J Oncol. 2015;46(1):414-22.

333. Zeissig Y, Petersen BS, Milutinovic S, Bosse E, Mayr G, Peuker K, Hartwig J, Keller A, Kohl M, Laass MW, Billmann-Born S, Brandau H, Feller AC, Röcken C, Schrappe M, Rosenstiel P, Reed JC, Schreiber S, Franke A, Zeissig S. XIAP variants in male Crohn’s disease. Gut. 2015;64(1):66-76.

332. Röcken C. Pathologische HER2-Diagnostik beim Magenkarzinom. In: Kurbacher CM (Hrsg.). Grundlagen und moderne Aspekte der HER2-Diagnostik. UNI-MED, Bremen, 2015; S. 66-72

331. von Schönfels W, Patsenker E, Fahrner R, Itzel T, Hinrichsen H, Brosch M, Erhart W, Gruodyte A, Vollnberg B, Richter K, Landrock A, Schreiber S, Brückner S, Beldi G, Sipos B, Becker T, Röcken C, Teufel A, Stickel F, Schafmayer C, Hampe J.Metabolomic tissue signature in human non-alcoholic fatty liver disease identifies protective candidate metabolites. Liver Int. 2015;35(1):207-14.

330. Kollmer J, Hund E, Hornung B, Hegenbart U, Schönland SO, Kimmich C, Kristen AV, Purrucker J, Röcken C, Heiland S, Bendszus M, Pham M. In vivo detection of nerve injury in familial amyloid polyneuropathy by magnetic resonance neurography. Brain. 2015;138:549-62.

329. Behrens HM, Warneke V, Böger C, Garbrecht N, Jüttner E, Klapper W, Mathiak M,  Oschlies I, Rudolph U, Stuhlmann-Laeisz C, Trick D, Röcken C, Hufnagl P. Reproducibility of Her2/neu scoring in gastric cancer and assessment of the 10% cut-off rule. Cancer Med. 2015;4(2):235-44.

328. Blank N, Hegenbart U, Lohse P, Beimler J, Röcken C, Ho AD, Lorenz HM, Schönland SO. Risk factors for AA amyloidosis in Germany. Amyloid. 2015;22(1):1-7

327. Kristen AV, Rinn J, Hegenbart U, Lindenmaier D, Merkle C, Röcken C, Hardt S, Giannitsis E, Katus HA. Improvement of risk assessment in systemic light-chain amyloidosis using human placental growth factor. Clin Res Cardiol. 2015;104:250-7.

326. Böger C, Warneke VS, Behrens HM, Kalthoff H, Goodman SL, Becker T, Röcken C. Integrins αvβ3 and αvβ5 as prognostic, diagnostic and therapeutic targets of gastric cancer. Gastric Cancer. 2015 Oct;18(4):784-95.

2014

325. Schänzer A, Kimmich C, Röcken C, Haverkamp T, Weidner I, Acker T, Krämer HH. A woman with a rare p.Glu74Gly transthyretin mutation presenting exclusively with a rapidly progressive neuropathy: a case report. J Med Case Rep. 2014 Dec 4;8(1):403.

324. Horvat S, Erhart W, Brosch M, Ammerpohl O, von Schönfels W, Ahrens M, Heits N, Bell J,  Spector TD, Deloukas P, Siebert R, Sipos B, Becker T, Röcken C, Schafmayer C, Hampe J. Obesity accelerates epigenetic aging of human liver. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15538-43.

323. Hess K, Böger C, Behrens HM, Röcken C. Correlation between the expression of integrins in prostate cancer and clinical outcome in 1284 patients. Ann Diagn Pathol. 2014;18(6):343-50.

322. Röcken C, Höfler H, Hummel M, Meyermann R, Zietz C, Schirmacher P. Participation in and support of clinical studies and other scientific investigations - Statement of the German Society for Pathology. Pathol Res Pract. 2014;210(11):705-12.

321. Bauer R, Dikow N, Brauer A, Kreuter M, Buss S, Evers C, Röcken C, Schnabel PA, Hinderhofer K, Ehlermann P, Katus HA, Kristen AV. The "Wagshurst study": p.Val40Ile transthyretin gene variant causes late-onset cardiomyopathy. Amyloid. 2014;21(4):267-75.

320. Ingold B, Behrens HM, Balschun K, Haag J, Krüger S, Becker T, Röcken C. HER2/neu testing in primary colorectal carcinoma. Br J Cancer. 2014;111(10):1977-84.

319. Moehler M, Baltin CT, Ebert M, Fischbach W, Gockel I, Grenacher L, Hölscher AH, Lordick F, Malfertheiner P, Messmann H, Meyer HJ, Palmqvist A, Röcken C, Schuhmacher C, Stahl M, Stuschke M, Vieth M, Wittekind C, Wagner D, Mönig SP. nternational comparison of the German evidence-based S3-guidelines on the diagnosis and multimodal treatment of early and locally advanced gastric cancer, including adenocarcinoma of the lower esophagus. Gastric Cancer. 2014 Sep 7. DOI 10.1007/s10120-014-0403-x.

318. Kristen AV, Biener M, Hegenbart U, Hardt S, Schnabel PA, Röcken C, Schönland SO, Katus HA, Giannitsis E. Evaluation of the clinical use of midregional pro-atrial natriuretic peptide (MR-proANP) in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP) for risk stratification in patients with light-chain amyloidosis. Int J Cardiol. 2014;176(3):1113-5.

317Röcken C (2014) Endokrinium. In: Kirchner T, Müller-Hermelink K, Roessner A (eds) Grundmann Kurzlehrbuch Pathologie. Kapitel 18, 12. Aufl. Urban & Fischer, München, pp elektronisch: www.mediscript-online. de

316. Marczynski-Bühlow M, Gro J, Berndt R, Röcken C, Wedel T, Böttner M, Cremer J, Lutter G, Petzina R. Comparison of Different Resection Tools for Human Calcified Aortic Valves. Innovations (Phila). 2014;9(4):312-6.

315. Fritscher-Ravens A, Schuppan D, Ellrichmann M, Schoch S, Röcken C, Brasch J, Bethge J, Böttner M, Klose J, Milla PJ. Confocal endomicroscopy shows food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome. Gastroenterology. 2014;147(5):1012-1020.

314. Kristen AV, Rosenberg M, Lindenmaier D, Merkle C, Steen H, Andre F, Schönland SO, Schnabel PA, Schuster T, Röcken C, Giannitsis E, Katus HA, Frey N.Osteopontin: a novel predictor of survival in patients with systemic light-chain amyloidosis. Amyloid. 2014;21(3):202-10

313. Berndt R, Heneweer C,·Riedel C, Schäfer JP, Petzina R, Marczynski-Bühlow M, Hess K, Röcken C, Cremer J, Lutter G, Groß J. Laserassistierte Thrombolyse der tiefen Bein und Beckenvenenthrombose. Gefässchirurgie 2014;19:226–231

312. Helm O, Mennrich R, Petrick D, Goebel1 L, Freitag-Wolf S, Röder C, Kalthoff H, Röcken C, Sipos B, Kabelitz B, Schäfer H, Oberg HH, Wesch D, Sebens S. Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma. PLoS One. 2014;9(5):e94357.

311. Grage-Griebenow E, Jerg E, Gorys A, Wicklein D, Wesch D, Freitag-Wolf S, Goebel L, Vogel I, Becker T, Ebsen M, Röcken C, Altevogt P, Schumacher U, Schäfer U, Sebens S. L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression. Mol Oncol. 2014;8(5):982-97.

310. Avsar Y, Spieker T, Kabar I, Röcken C, Wolters H, Schmidt H. ApoAIL75P amyloidosis causes cirrhosis-like appearance of the liver in the absence of laboratory or clinical signs of hepatic dysfunction. Amyloid 2014;21(2):128-30.

309. Egberts F, Krüger S, Behrens HM, Bergner I, Papaspyrou G, Werner JA, Alkatout I, Haag J, Hauschild A, Röcken C. Melanomas of unknown primary frequently harbour TERT-promoter mutations. Melanoma Res. 2014;24(2):131-6

308. Helm O, Held-Feindt J, Grage-Griebenow E, Reiling N, Ungefroren H, Vogel I, Krüger U, Becker T, Ebsen M, Röcken C, Kabelitz D, Schäfer H, Sebens S. Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis. Int J Cancer. 2014;135(4):843-61.

307. Oberg HH, Peipp M, Kellner C, Sebens S, Krause S, Petrick D, Adam-Klages S, Röcken C, Becker T, Vogel I, Weisner D, Freitag-Wolf S, Gramatzki M, Kabelitz D, Wesch D. Novel bispecific antibodies increase gd T-cell cytotoxicity against pancreatic cancer cells. Cancer Res. 2014;74(5):1349-60

306. Renker T, Haneke E, Röcken C, Borradori L. Systemic light-chain amyloidosis revealed by progressive nail involvement, diffuse alopecia and sicca syndrome: report of an unusual case with a review of the literature. Dermatology. 2014;228(2):97-102.

305. Ungefroren H, Sebens S, Giehl K, Helm O, Groth S, Fändrich F, Röcken C, Sipos B, Lehnert H, Gieseler F. Rac1b negatively regulates TGF-beta1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling. Oncotarget. 2014;5(1-1):277-90.

304. Egberts F, Bergner I, Krüger S, Haag J, Behrens HM, Hauschild A, Röcken C. Metastatic melanoma of unknown primary resembles the genotype of cutaneous melanomas. Ann Oncol. 2014;25(1):246-50.

303. Böger C, Kalthoff H, Goodman SL, Behrens HM, Röcken C. Integrins and their ligands are expressed in non-small cell lung cancer but not correlated with parameters of disease progression. Virchows Arch. 2014;464(1):69-78.

302. Haselmann V, Kurz A, Bertsch U, Olempska-Müller M, Fritsch J, Pickl A, Engler C, Fleig B, Schmidt H, Häsler R, Annewanter F, Röder C, Bernt A, Gelhaus C, Böger C, Knippschild U, Röcken C, Schütze S, Walczak H, Janssen O, Wulczyn FG, Wajant H, Kalthoff H, Trauzold A. Nuclear death receptor TRAIL-R2 enhances tumor malignancy by inhibiting let-7 maturation. Gastroenterology. 2014;146(1):278-90

301. Koinzer S, Bajorat S, Hesse C, Caliebe A, Bever M, Brinkmann R, Röcken C, Roider J. Calibration of histological retina specimens after fixation in Margo's solution and paraffin embedding to in-vivo dimensions, using photography and optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 2014;252(1):145-53.

300. Quabius E, Möller P, Haag J, Pfannenschmidt S, Hedderich J, Görögh T, Röcken C, Hoffmann  M. The role of the antileukoprotease SLPI in smoking-induced human papillomavirus-independent head and neck squamous cell carcinomas. Int J Cancer. 2014;134(6):1323-34.

299. Tsourdi E, Därr R, Wieczorek K, Röcken C, Ehehalt F, Conrad K, Platzbecker U, Hofbauer LC. Macroglossia as the only presenting feature of amyloidosis due to MGUS. Eur J Haematol. 2014;92(1):88-9.


2013

298. Röcken C, Höfler H, Hummel M, Meyermann R, Zietz C, Schirmacher P (2013) Gewebe-Biobanking im Spannungsfeld von Forschung und Versorgung. In: Hummel M, Illig T, Jahns R, Kiehntopf M, Krawczak M, Schirmacher P, Semler SC (Hrsg.) Zukunft der Biobanken-Forschung in Deutschland: Vernetzung, Kollaborationen und Strukturaufbau; Session 1; S. 15-23. Akademische Verlagsgesellschaft AKA GmbH, Berlin, Deutschland.

297. Röcken C (2013) Diagnosis and typing of amyloid in the Amyloid Registry Kiel. In: Hazenberg BPC, Bijzet J (Hrsg.) Proceedings of the XIIIthe international Symposium on Amyloidosis; Section IV; S. 145-150. GUARD Groningen, Niederlande.

296. Seufferlein T, Porzner M, Becker T, Budach V, Ceyhan G, Esposito I, Fietkau R, Follmann M, Friess H, Galle P, Geißler M, Glanemann M, Gress T, Heinemann V, Hohenberger W, Hopt U, Izbicki J, Klar E, Kleeff J, Kopp I, Kullmann F, Langer T, Langrehr J, Lerch M, Löhr M, Lüttges J, Lutz M, Mayerle J, Michl P, Möller P, Molls M, Münter M, Nothacker M, Oettle H, Post S, Reinacher-Schick A, Röcken C, Roeb E, Saeger H, Schmid R, Schmiegel W, Schoenberg M, Siveke J, Stuschke M, Tannapfel A, Uhl W, Unverzagt S, van Oorschot B, Vashist Y, Werner J, Yekebas E. S3-Leitlinie zum exokrinen Pankreaskarzinom. Z Gastroenterol. 2013; 51(12): 1395-1440.

295. Röcken C. Die nichtalkoholische Steatohepatitis als viszerale Manifestation des metabolischen Syndroms. Gastroenterologe. 2013;8:517–524.

294. Dohrn MF, Röcken C, De Bleecker J, Martin JJ, Vorgerd M, Van den Bergh PY, Ferbert A, Hinderhofer K, Schröder JM, Weis J,  Schulz JB, Claeys KG. Diagnostic hallmarks and pitfalls in late-onset progressive transthyretin related amyloid-neuropathy. J Neurol. 2013 Dec;260(12):3093-108.

293. von Schönfels W, von Kampen O, Patsenker E, Stickel F, Schniewind B, Hinz S, Ahrens M, Balschun K, Egberts JH, Richter K, Landrock A, Sipos B, Will O, Huebbe P, Schreiber S, Nothnagel M, Röcken C, Rimbach G, Becker T, Hampe J, Schafmayer C. Metabolic signature of electrosurgical liver dissection. PLoS One. 2013 Sep 13;8(9):e72022. doi: 10.1371/journal.pone.0072022.

292.  Warneke V, Behrens HM, Haag J, Krüger S, Simon E, Matthiak M, Ebert MPA, Röcken C. Members of the EpCAM signaling pathway are expressed in gastric cancer tissue and are correlated with patient prognosis. Br J Cancer. 2013 Oct 15;109(8):2217-27.

291. Denkert C, Erbersdobler A, Kellner U, Kristiansen G, Lage H, Petersen I, Röcken C, Stenzinger A, Turzynski A, Weichert W. Herzlichen Glückwunsch zum Geburtstag, lieber Herr Dietel! Pathologe. 2013;34(5):389-90.

290. Ahrens M, Ammerpohl O, von Schönfels W, Kolarova J, Bens S, Itzel T, Teufel A, Herrmann A, Brosch M, Hinrichsen H, Erhart W, Egberts J, Sipos B, Schreiber S, Hä sler R, Stickel F, Becker T, Krawczak M, Röcken C, Siebert R, Schafmayer C,Hampe J. DNA methylation analysis in non-alcoholic fatty liver disease suggests distinct disease-specific and molecular remodelling signatures after bariatric surgery. Cell Metab. 2013;18(2):296-302

289. Röcken C. Wege zur personalisierten Medizin beim Magenkarzinom. Der Pathologe. 2013 Sep;34(5):403-12

288. Röcken C, Höfler H, Hummel M, Meyermann R, Zietz C, Schirmacher P. Beteiligung und Unterstützung klinischer Studien und anderer wissenschaftlicher Untersuchungen - Stellungnahme der Deutschen Gesellschaft für Pathologie e. V.. Der Pathologe. 2013;34(5):466-75

287. Warneke V, Behrens HM, Haag J, Balschun K, Böger C, Becker T, Ebert MPA, Lordick F, Röcken C. Prognostic and putative predictive biomarkers of gastric cancer for personalized medicine. Diagn Mol Pathol. 2013;22(3):127-37

286. Röcken C, Rüdiger T, Koch B. Zertifizierte Fortbildung in Der Pathologe. Der Pathologe. 2013; 34:292

285. Mathiak M, Warneke V, Schem C, Röcken C. Klinische und morphologische
Parameter beim Mammakarzinom - Molekulare Subtypen. Der Gynäkologe. 2013;46:369-376.

284. Schreml S, Weber BH, Schröder J, Siegmund H, Schaller J, Vogt T, Landtahler M, Schönbuchner I, Röcken C, Babilas P. Familial primary localized cutaneous amyloidosis
with a Pro694Leu oncostatin M receptor-ß mutation. Clin Exp Dermatol. 2013 May 20. doi: 10.1111/ced.12160

283. Röcken C. Klinische Studien in der Onkologie: eine Herausforderung für die klinische und akademische Pathlogie. Dtsch Med Wochenschr. 2013;138(20):1073-6

282. Hitkova I, Yuan G, Anderl F, Gerhard M, Kirchner T, Reu S, Röcken C, Schäfer C, Schmid RM, Vogelmann R, Ebert MP, Burgermeister E. Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. PLoS Pathogens. 2013;9(4):e1003251

281. Lordick F, Röcken C. The identification of predictive factors for peri-operative chemotherapy in esophago-gastric cancer. Ann Oncol. 2013;24(5):1135-8

280. Hoffmann M, Quabius ES, Tribius S, Hedebrand L, Görögh T, Halec G, Kahn T, Hedderich J, Röcken C, Haag J. Waterboer T, Schmitt M, Giuliano AR, Kast WM. Human papillomavirus infection in head and neck cancer: the role of the secretory leukocyte protease inhibitor. Onco Repl. 2013;29(5):1962-8

279. Böger C, Kalthoff H, Goodman SL, Röcken. Validation and comparison of anti-αvβ3 and anti-αvβ5 rabbit monoclonal versus murine monoclonal antibodies in four different tumor entities. Appl Immunohistochem Mol Morphol. 2013 Dec;21(6):553-60.

278. Gioeva Z, Urban P, Meliss RR, Haag J, Axmann HD, Siebert F, Beckker K, Radtke HG, Röcken C. ATTR amyloid in the carpal tunnel ligament is frequently of wildtype transthyretin origin. Amyloid. 2013 Mar;20(1):1-6.

277. Warneke V, Behrens HM, Böger C, Becker T, Lordick F, Ebert M, Röcken C. Her2/neu-testing in gastric cancer – evaluating the risk of sampling errors. Ann Oncol 2013 Mar;24(3):725-33.

276. Yuan G, Gruner-Regel I, Lian F, Friedrich T, Hofheinz R, Langer R, Röcken C, Zimmermann W, Schmid RM, Ebert MPA, Burgermeister E. WNT6 is a novel target gene of caveolin-1 promoting chemoresistance to epirubicin in human gastric cancer cells. Oncogene. 2013 Jan 17;32(3):375-87.

275. Kristen AV, Haufe S, Schönland SO, Hegenbart U, Schnabel PA, Röcken C, Hardt S, Lohse P, Ho AD, Haberkorn U, Dengler TJ, Altland K, Katus HA. Skeletal scintigraphy indicates disease severity of cardiac involvement in patients with senile systemic amyloidosis. Int J Cardiol. 2013 Apr 5;164(2):179-84

2012

274. Mayr M, Becker K, Schulte N, Belle S, Hofheinz R, Krause A, Schmid RM, Röcken  C, Ebert MP. Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma. BMC Cancer 2012, 12:587

273. Stallmach, Spinas GA, Röcken C (2012) Stoffwechselerkrankungen. In: Böcker W, Denk H, Heitz PU, Höfler G, Kreipe H, Moch H (eds) Pathologie., 5., vollständig überarb. Aufl. , Urban & Fischer, München, pp 913-932

272. Röcken C (für die deutsche Ausgabe) (2012) Atlas der Urinsedimente und Nierenbiopsien. In: Dietel M, Suttorp N, Zeitz M (eds) Harrisons Innere Medizin. Deutsche Ausgabe in 4 Bänden., Kapitel 44 e14, 18.Aufl. ABW Wissenschaftsverlag, Berlin, pp elektronisch: www.harrisons-online.de

271. Laghi L, Beghelli S, Spinelli A, Bianchi P, Basso G, Di Caro G, Brecht A, Celesti G, Turri G, Bersani S, Schumacher G, Röcken C, Gräntzdörffer I, Roncalli M, Zerbi A, Neuhaus P, Bassi C, Montorsi M, Scarpa A, Malesci A.Irrelevance of Microsatellite Instability in the Epidemiology of Sporadic Pancreatic Ductal Adenocarcinoma. PLoS One. 2012;7(9):e46002.

270. Röcken C, Warneke V. Molekulare Pathologie des Magenkarzinoms. Der Pathologe. 2012;33 Suppl 2:235-40.

269. Steffen J, Simon E, Warneke V, Balschun K, Ebert M, Röcken C. LGR4 and LGR6 are differentially expressed and of putative tumor biological significance in gastric carcinoma. Virchows Arch. 2012;461(4):355-65.

268. Eckardt AJ, Adler A,  Gomes EM, Jenssen C, Siebert C, Gottschalk U, Koch M, Röcken C, Rösch T. Endosonographic Large-Bore Biopsy of Gastric Submucosal Tumors:  A Prospective Multicenter Study. Eur J Gastroenterol Hepatol. 2012;24(10):1135-44.

267. Tribius S, Hoffmann AS, Bastrop S, Görögh T, Haag J, Röcken C, Clauditz T, Grob T, Wilczak W, Tennstedt P, Borcherding A, Petersen C, Hoffmann M. HPV status in patients with head and neck of carcinoma of unknown primary site: HPV, tobacco smoking, and outcome? Oral Oncol. 2012;48(11):1178-84.

266. Zeissig S, Murata K, Sweet L, Publicover J, Hu Z, Kaser A, Bosse E, Iqbal J, Hussain MM, Balschun K, Röcken C, Arlt A, Günther R, Hampe J, Schreiber S, Baron JL, Moody B, Liang TJ, Blomberg R. Hepatitis B virus–induced lipid alterations contribute to natural killer T cell–dependent protective immunity. Nat Med. 2012;18(7):1060-8.

265. Hagmeyer L, Stieglitz S, Röcken C, Randerath W. Amyloidose in der Pneumologie. Pneumologie. 2012;66(8):483-92.

264. Kristen AV, Lehrke S, Buss S, Mereles D, Steen H, Ehlermann P, Hardt S,Giannitsis E, Schreiner R, Haberkorn U, Schnabel PA, Linke RP, Röcken C, Wanker EE, Dengler TJ, Altland K, Katus HA. Green Tea Halts Progression of Cardiac Transthyretin Amyloidosis – an Observational Report. Clin Res Cardiol. 2012;101(10):805-13.

263. Simon E, Petke D, Böger C, Behrens HM, Warneke V, Ebert M, Röcken C. The Spatial Distribution of LGR5+ Cells Correlates With Gastric Cancer Progression. PLoS One. 2012;7(4):e35486.

262. Hoffmann M, Tribius S, Quabius ES, Henry H, Pfannenschmidt D, Burkhardt C, Görögh T, Halec G, Hoffmann AS, Kahn T, Röcken C, Haag J, Waterboer T, Schmitt M. HPV DNA, E6*I-mRNA expression and p16INK4A immunohistochemistry in head and neck cancer – how valid is p16INK4A as surrogate marker? Cancer Lett. 20121; 323(1):88-96.

261. Prade E, Tobiasch M, Hitkova I, Schäffer I, Lian F, Xing X, Tänzer M, Rauser S, Walch A, Feith M, Post S, Röcken C, Schmid R, Ebert M, Burgermeister E. Bile acids down-regulate caveolin-1 in esophageal epithelial cels through sterol responsive elemend-binding protein. Mol Endocrinol. 2012;26(5):819-32.

260. Regel I, Merkl L, Friedrich T, Burgermeister E, Zimmermann W, Einwächter H, Herrmann K, Langer R, Röcken C, Hofheinz R, Schmid R, Ebert MP.  The pan-histone deacetylase inhibitor panobinostat (lbh589) sensitizes gastric cancer cells to anthracyclines via induction of cited2. Gastroenterology. 2012;143(1):99-109.e10.

259. Grenacher L, Schwarz M, Lordick F, Röcken C, Mönig S,  Ebert M, Möhler M, Kauczor HU. Aktualisierte S3-Leitlinie zur Diagnostik und Therapie des Magenkarzinomes. Rofo. 2012;184(8):706-12.

258. Lupp A, Nagel F, Doll C, Röcken C, Evert M, Mawrin C, Saeger W, Schulz S. Reassessment of sst(3) Somatostatin Receptor Expression in Human Normal and Neoplastic Tissues Using the Novel Rabbit Monoclonal Antibody UMB-5. Neuroendocrinology. 2012;96(4):301-10.

257. Brosch M, von Schonfels W, Ahrens M, Nothnagel M, Krawczak M, Laudes M, Sipos B, Becker T, Schreiber S, Röcken C, Schafmayer C, Hampe J. SFRS10—A Splicing Factor Gene Reduced in Human Obesity? Cell Metab. 2012;15(3):265-6.

256. Harder J,Ihorst G, Heinemann V, Hofheinz R, Moehler M, Buechler P, Kloeppel G, Röcken C, Bitzer M, Boeck S, Endlicher E, Reinacher-Schick A, Schmoor C, Geissler M. Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancer. Br J Cancer. 2012;106(6):1033-8.

255. Ehling R, Helbok R, Beer R, LacknerP, Broessner G, Pfausler B, Röcken C,Aguzzi  A, Chemelli A, Schmutzhard E. Recurrent intracerebral haemorrhage after coitus: a case report of sporadic cerebral amyloid angiopathy in a younger patient. Eur J Neurol. 2012 Mar;19(3):e29-31.

254. Kristen AV, Röcken C. Amyloidose des Herzens. Pathologe. 2012;33(3):236-44.

253. Kreipe HH, Röcken C. Qualitätssicherungund Referenzbeurteilung in der Onkologischen Pathologie. Forum 2012;27:33-37

252. Ebert MPA,Tänzer M, Balluff B, Burgermeister E, Kretzschmar AK, Hughes DJ, Tetzner R,Lofton-Day C, Rosenberg R, Reinacher-Schick AC, Schulmann K, Tannapfel A,Hofheinz R, Röcken C, Keller G, Langer R, Specht K, Porschen R,Stöhlmacher-Williams J, Schuster T, Struble RG, Schmid RM TFAP2E-DKK4 and Chemoresistance in Colorectal Cancer. N. Engl. J. Med. 2012; 366:44-53

251. Schönland S, Hegenbart U, Bochtler T, Mangatter A, Hansberg O, Ho AD, Lohse P, Röcken C. Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients. Blood 2012;119(2):488-93.

250. Ammerpohl  O, Pratschke J, Schafmayer C, Haake A, FaberW, von Kampen O, Brosch M, von Schoenfels W, Sipos B, Balschun K, Röcken C,Arlt A, Schniewind B, Grauholm J, Kalthoff H, Neuhaus P, Stickel F, SchreiberS, Becker T, Siebert R, Hampe J. DistinctDNA methylation patterns in cirrhotic liver and hepatocellular carcinoma. Int J Cancer. 2012;130(6):1319-28.


2011

249. Warneke VS, Behrens HM, Hartmann J, Held H, Becker T, Schwarz NT, Röcken C. Reply to A. Biondi et al and J. Deng et al. J Clin Oncol. 2011;29(32):4340-4342

248. Balschun K, Wenke AK, Röcken C, Haag J. Detection of KRAS and BRAF mutations in advanced colorectal cancer by allele-specific single-base primer extension. Expert Rev Mol Diagn. 2011;11(8):799-802.

247. Kristen AV, Katus HA, Röcken C, Altland K. Therapie der Thransthyretin-Amyloidose: Grüner Tee als Oprion? DNP - Der Neurologe & Psychiater 2011;12:7-8

246. Balschun K, Röcken C. Filiforme Polypose. Eine seltene Komplikation bei Patienten mit chronisch entzündlicher Darmerkrankung. Gastroenterologie up2date. 2011;7:166-170.

245. Röcken C. Die Rolle der Mikro-RNA bei der Entstehung onkologischer Erkrankungen. Der Onkologe. 2011;17(6):487-494

244. Balschun K, Haag J, Wenke AK, von Schönfels W, Schwarz NT, Röcken C. KRAS-, NRAS-, PIK3CAexon 20- and BRAF-genotype in synchronousand metachronous primary colorectal cancers – diagnostic and therapeuticimplications. J Mol Diagn. 2011;13(4):436-45

243. Burgermeister E, Friedrich T, Hitkova I, Gruner I, EinwächterH, Zimmermann W, Röcken C, Perren A,Wright MB, Schmid RM, Seger R, Ebert MPA. The ras inhibitors caveolin-1 and docking protein-1 activate PPARgammathrough spatial relocalization at helix-7 of its ligand-binding domain. Mol Cell Biol. 2011;31(16):3497-510

242. Lian F, Xing X, Yuan G, Schäfer C, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB, Schmid RM, Ebert MPA, Burgermeister E. Farnesoid X receptor protects human and murine gastric epithelial cells against inflammation-induced damage. Biochem J. 2011;438(2):315-23.

241. Warneke V, Behrens HM, Hartmann JT, Held H, Becker T,Schwarz NT, Röcken C. A cohort study based on the 7th edition of the TNMclassification for gastric cancer: proposal of a new staging system. J Clin Oncol. 2011;29(17):2364-71

240. Cordes C, Häsler R, Werner C,Görögh T, Röcken C, Hebebrand L,Kast WM, Hoffmann M, Schreiber S, Ambrosch. The level of secretory leukocyte protease inhibitor is decreased in metastatic headand neck squamous cell carcinoma. Int J Oncol. 2011;39(1):185-91

239. Möhler M etal. S3-Leitlinie Magenkarzinom. Diagnostik und Therapieder Adenokarzinome des Magens und ösophagogastralen Übergangs. Z Gastroenterol. 2011;49(4):461-531

238. Stecker K, Vieth M, Koschel A, Wiedenmann B, Röcken C, Anders M. Impact of the coxsackievirus and adenovirus receptor on the adenoma-carcinoma sequence of colon cancer. Br J Cancer. 2011;104(9):1426-33

237. Schmuck R, Warneke V, Behrens HM, Weichert W, Röcken C. Genotypic and phenotypic characterization of the side population of gastric cancer. Am J Pathol. 2011;178(4):1792-1804

236. Kieninger B, Gioeva Z, Krüger S, Westermark G, Friedrich RP, Fändrich M, Röcken C.  PTAA and B10: new approaches to amyloid detecteion in tissue. Evaluation of amyloid detection in tissue with a conjugated polyelectrolyte and a fibril-specific antibody fragment. Amyloid. 2011;18(2):47-52

235. Haupt C, Bereza M, Kumar ST, Kieninger B, Morgado I, HortschanskyP, Fritz G, Röcken C, Horn C, FändrichM. Pattern recognition with a fibril-specific antibody fragment reveals the surfacevariability of natural amyloid fibrils. J Mol Biol. 2011;408(3):529-40

234. Jann H, Roll S, Couvelard A, Hentic O, Pavel M, Müller-Nordhorn J, Koch M, Röcken C, Rindi G, Ruszniewski P, Wiedenmann B, Pape UF. Neuroendocrine tumors of mid- and hindgut origin:TNM-classification determines clinical outcome. Cancer. 2011;117(15):3332-41

233. Kohler I, Jacob D, Budzies J, Lehmann A, Weichert W, Schulz S, Neuhaus P, Röcken C. Phenotypic and genotypic characterization of carcinomas of the papilla of Vater has prognostic and putative therapeutic implications. Am J Clin Pathol. 2011;135(2):202-11

232. Herpel E, Röcken C, Manke H, Schirmacher P, Flechtenmacher C. Letter to the editor-reply to comments of Carter et al. Virchows Arch 2011;458(2):249-50

231. Kasajima A, Pavel M, Darb-Esfahani S,Noske A, Stenzinger A, Sasano H, Dietel M, Denkert C, Röcken C, Wiedenmann B, Weichert W. mTOR expression and activity patterns in gastroenteropancreatic neuroendocrine tumors. Endocr Relat Cancer.  2011;18(1):181-92.

2010

230. Gabbert HE, Röcken C. Her2. Ein neuer prädiktiver Biomarker in der Behandlung des metastasierten Magenkarzinoms. Forum. 2010;25:48-49

229. Röcken C, Rüschoff J. Identifikationtherapeutischer Zielstrukturen: EGFR, Her2 und EpCamIn: Lordick F(Hrsg.). Biologie und zielgerichtete Therapie des Magenkarzinoms. UNI-MED,Bremen, 2010; S. 38-45

228. Endo J, Röcken C, Lamb S, Harris RM, Bowen AR. Nodular amyloidosis in a diabetic patient with frequent hypoglycemia: sequela of repeatedly injecting insulin without site rotation. J Am Acad Dermatol. 2010;63(6):e113-4

227. Balluff B, Elsner M, Kowarsch A,Rauser S, Meding S, Schuhmacher C, Feith M, Herrmann K, Röcken C, Schmid RM, Höfler H, Walch A, Ebert MPA. Classification of HER2/neu status in gastric cancerusing a breats-cancer derived proteome classifier. J Proetome Res. 2010;9(12):6317-6322

226. Herpel E, Röcken C, Manke H, Schirmacher P,Flechtenmacher. Quality Management and Accreditation of Research Tissue Banks. Virchows Arch. 2010;457(6):741-7

225. Tchernitsa O, Kasajima A,Schäfer R, Kuban RJ, Ungethüm U, Györffy B, Neumann U, Simon E, Weichert W,Ebert MPA, Röcken C. Systematicevaluation of the miRNA-ome and downstream effects on mRNA expressionidentifies gastric cancer progression. J Pathol. 2010;222(3):310-9.

224. Lordick  F, Grenacher L, Röcken C, Ebert M, Moehler M, Schumacher G. Diagnostik und Therapie des Magenkarzinoms. Dtsch Med Wochenschr. 2010;135(34/35):1671-1682

223. Röcken C. Amyloid und Amyloidosen des Gastrointestinaltrakts. Verdauungskrankheiten. 2010;4:154-158

222. Berndt U, Philipsen L, Bartsch S, Hu Y, Röcken C, Wiedenmann B, Haemmerle M, Rösch T, Sturm A. Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma. Mol Cancer. 2010;9(1):177

221. Kristen AV, Giannitsis E, Schönland S, Hegenbart U, LehrkeS, Konstandin M, Lindenmaier D, Merkle C, Hardt C, Röcken C, Schnabel P, Ho A, Dengler T, Katus. Assessment of Disease Severity and Outcome in Patients with SystemicLight-Chain Amyloidosis by the High-sensitivity Troponin-T Assay. Blood. 2010;116(14):2455-61

220. Csepregi A, Ebert MP, Röcken C, Schneider-Stock R,Hoffmann J, Schulz HU, Roessner A, Malfertheiner P. Promotermethylation of CDKN2A and lack of p16 expression characterize patients withhepatocellular carcinoma. BMC Cancer. 2010;10(1):317

219. Schmeding M, Kienlein S, Röcken C, Neuhaus R, Neuhaus P, Heidenhain C, Neumann UP. ELISA-based detection of C4d after liver transplantation - a heplful tool for differential diagnosis between acute rejection and HCV-recurrence? Transpl Immunol. 2010;23(4):156-60

218. Ingold B, Simon E, Ungethüm U, Kuban RJ, Müller BM, Lupp A, Neumann U, Ebert MPA, Denkert C, Weichert W, Schulz S, Röcken C. Vascular CXCR4 expression – a novel antiangiogenic target in gastric cancer? PLoS One. 2010;5(4):e10087

217. Kieninger B, Eriksson M, Kandolf R, Schnabel P, Schönland S, Hegenbart U, Lohse P, Röcken C. Amyloid in endomyocardial biopsies.Virchows Archiv. 2010;456(5):523-32

216. Lupp A, Klenk C, Röcken C, Evert M, Mawrin C, Schulz S. Immunohistochemical identification of the PTHR1 parathyroid hormone receptor in normal and neoplastic human tissues. Eur J Endocrinol. 2010;162(5):979-86

215. Tänzer M, Balluff B, Distler J, Hale K, Leodolter A, Röcken C, Molnar B, Schmid R, Lofton-Day C, Schuster T, Ebert MPA. Performance of Epigenetic Markers SEPT9 and ALX4 in Plasma for Detection of Colorectal Precancerous Lesions. PLoS One 2010; 5(2): e9061.

214. Schmeding M, Rademacher S, Boas-Knoop S, Röcken C, Lendeckel U, Neuhaus P, Neumann UP. rHuEPo reduces ischemia-reperfusion injury and improves survival after transplantation of fatty livers in rats. Transplantation. 2010;89(2):161-8.

213. Nilsson KPR, Ikenberg K, Aslund A, Fransson S, Konradsson P, Röcken C, Moch H, Aguzzi A. Structural typing of systemic amyloidoses by luminescent conjugated polymer spectroscopy. Am J Pathol. 2010;176(2):563-74.

212. Röcken C, Manke H. Akkreditierung in der Pathologie. Der Pathologe. 2010;31(4):268-78

211. Weichert W, Schewe C, Lehmann A, Sers C, Denkert C, Budczies J, Stenzinger A, Joos H, Landt O, Heiser V, Röcken C, Dietel M. KRAS genotyping of paraffin embedded colorectal cancer tissue in routine diagnostics. Comparison of methods and impact of histology. J Mol Diagn. 2010;12(1):35-42

210. Kozian A, Schilling T, Röcken C, Breitling C, Hachenberg T, Hedenstierna G. Increased alveolar damage after mechanical ventilation ion a porcine model of thoracic surgery. J Cardiothorac Vasc Anesth. 2010;24(4):617-623

209. Gräntzdörffer I, Yumlu S, Gioeva Z, von Wasielewski R, Ebert MP, Röcken C. Comparison of different tissue sampling methods for protein extraction from formalin-fixed and paraffin-embedded tissue specimens. Exp Mol Pathol. 2010; 88:190-196

2009

208. Kamphues C, Bova R, Röcken C, Neuhaus P, Pratschke J, Neumann UP. Safety of mycophenolate mofetil monotherapy in patients after liver transplantation. Ann. Transplantat. 2009;14(4):40-6.

207. Franke K, Carl-McGrath S, Röhl FW, Lendeckel U, Ebert M, Tänzer M, Pross M, Röcken C. Differential expression of SPARC in intestinal type gastric cancer correlates with tumor progression and nodal spread. Transl Oncol. 2009;2(4):310-20.

206. Kamphues C, Lotz K, Röcken C, Berg T, Eurich D, Pratschke J, Neuhaus P, Neumann UP. Chances and limitations of non-invasive tests in the assessment of liver fibrosis in liver transplant patients. Clin Transplant. 2010;24(5):652-9

205. Ingold B, Schulz S, Budzies J, Neumann U, Ebert M, Weichert W, Röcken C. The role of vascular CXCR4 expression in colorectal carcinoma. Histopathology. 2009;55(5):576-586.

204. Kristen AV, Sack FU, Schönland SO, Hegenbart U, Helmke BM, Koch A, Schnabel PA, Röcken C, Hardt S, Remppis A, Goldschmidt H, Karck M, Ho AD, Katus HA, Dengler TJ. Staged heart transplantation and chemotherapy as treatment option in patients with severe cardiac light-chain amyloidosis. Eur J Heart Fail. 2009;11(10):1014-20.

203. Röcken C. Update – Immuhistologische Klassifikation der Amyloidosen. Der Pathologe. 2009;30 Suppl 2:121-3

202. Yumlu S, Barany R, Eriksson M, Röcken C. Localized insulin-derived amyloidosis in patients with diabetes mellitus: A report of four cases. Human Pathol. 2009;40(11):1655-60. Epub 2009 Aug 14.

201. Ng E, Tsang W, Ng SS, Jin H, Yu J, Li JJ, Röcken C, Ebert MPA, Kwok TT, Sung JJY. MicroRNA-143 targets DNA methytransferase 3A in colorectal cancer. Br J Cancer. 2009;101(4):699-706

200. von Hutten H, Mihatsch M, Lobeck H, Rudolph B, Eriksson M, Röcken C. Prevalence and origin of amyloid in kidney biopsies. Am J Surg Pathol. 2009;33(8):1198-205

199. Neumann U, Thelen A, Röcken C, Bahra M, Riess H, Jonas S, Schmeding M, Pratschke J, Bova R, Neuhaus P. Non-response to preoperative chemotherapy does not preclude long-term survival after liver resection in patients with colorectal liver metastases. Surgery. 2009 Jul;146(1):52-9. Epub 2009 Apr 21.

198. Babilas P, Fiebig B, Aslanidis C, Hansen J, Röcken C, Schröder J, Schmitz G, Weber B, Landtaler M, Vogt T. Identification of an oncostatin M receptor mutation associated with familial primary cutaneous amyloidosis. Br J Dermatol. 2009 Oct;161(4):944-7. Epub 2009 May 21. No abstract available

197. Carl-McGrath S, Gräntzdörffer I, Ebert MPA, Röcken C. Angiotesnin II-generating enzymes, angiotensin-converting enzyme (ACE) and mast-cell chymase (CMA1) in gastric inflammation may be regulated by pylori H. and associated cytokines. Pathology. 2009 May 6:1-9

196. Gioeva Z, Kieninger B, Röcken C. Amyloidosis in liver biopsies. Der Pathologe. 2009 May;30(3):240-5

195. Le Coutre P, Meisel H, Hofmann J, Röcken C, Vuong LG, Neuburger S, Hemmati PG, Dörken B, Arnold R. Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukemia after allogeneic stem cell transplantation. Gut. 2009 May;58(5):699-702

194. Carl M, Röcken C, Spuler S. Amyloidose bei Muskeldystrophie. Der Pathologe. 2009 May;30(3):235-9

193. Eriksson M, Schönland S, Yumlu S, Hegenbart U, Gioeva Z, Lohse P, Büttner J, Schmidt H, Röcken C. Hereditary apolipoprotein AI-associated amyloidosis in surgical pathology specimens: Identification of three novel mutations in the APOAI-gene. J Mol Diagn. 2009 May; 11(3):257-62



192. Röcken C, Eriksson M. Amyloid und Amyloidosen. Der Pathologe. 2009 May;30(3):182-92

191. Röcken C. Amyloid und Amyloidosen in der Pathologe. Der Pathologe. 2009 May;30(3):173-4



190. Röcken C, Widulin N, Schnalke T. Die Amyloidosen des Berliner Medizinhistorischen Museums der Charité. Der Pathologe. 2009 May;30(3):226-34.

189.  Bukowska A, Röcken C, Erxleben M, Röhl FW, Huth C, Ebert MPA, Lendeckel U, Goette A. Atrial expression of endothelial nitric oxide synthase in patients with and without atrial fibrillation. Cardiovasc Pathol. 2009 Feb 10. [Epub ahead of print]

188. Xing X, Burgermeister E, Geisler F, Einwächter F, Fan L, Hiber M, Rauser S, Walch A, Röcken C, Ebeling M, Wright MB,  Schmid RM, Ebert MPA. Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy. Hepatology. 2009 Mar;49(3):979-88

187. Anders M, Vieth M, Röcken C, Ebert M, Pross M, Gretschel S, Schlag PM, Wiedenmann B, Kemmner W, Höcker M. Loss of coxsackie and adenovirus receptor contributes to gastric cancer progression. Br J Cancer. 2009 Jan 27;100(2):352-9. Epub 2009 Jan 13.

186. Yu J, Tao Q, Cheng YY, Lee KY, Ng SS, Cheung KF, Tian L, Rha SY, Neumann U, Röcken C, Ebert MPA, Chan FKL, Sung JJY. Promoter methylation of a Wnt/b-catenin signaling antagonist DKK3 is associated with poor survival of gastric cancer. Cancer. 2009 Jan 1;115(1):49-60.

185. Kühlmann UC, Chwieralski CE, van den Brule S, Röcken C, Reinhold D, Welte T, Bühling F. Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases. Life Sci. 2009 Jan 2;84(1-2):1-11. Epub 2008 Oct 17

184. Eriksson M, Büttner J, Todorov T, Yumlu S, Schönland S, Hegenbart U, Kristen AV, Dengler T, Lohse P, Haas J, Helmke B, Schmidt H, Röcken C. Prevalence of germline mutations in the TTR gene in a consecutive series of surgical pathology specimens with ATTR amyloid. Am J Surg Pathol. 2009 Jan;33(1):58-65.

183. Erbersdobler A, Kollermann J, Graefen M, Röcken C, Schlomm T. Seminal Vesicle amyloidosis does not protect from invasion by prostate cancer.BJU Int. 2009 Feb;103(3):324-6. Epub 2008 Sep 3

182. Mantke R, Schubert D, Röcken C, Paege I, Halangk W, Peters B, Lippert H, Schulz HU.  Caerulein or taurocholate induced enzymatic and histologic alterations in the isolated perfused rat pancreas. 2009 Mar;394(2):363-9. Epub 2008 Aug 9

181. Kamphues CH, Röcken C, Neuhaus P, Neumann UP. Non-functioning, malignant pancreatic neuroendocrine tumour (PNET): a rare entity during pregnancy. Langenbecks Arch Surg. 2009 Mar;394(2):387-91. Epub 2008 May 30


2008

180. McGough JM, Yang D, Huang S, Georgi D, Hewitt SM, Röcken C, Tänzer M, Ebert MPA, Liu K. DNA Methylation Represses IFN-{gamma}-Induced and Signal Transducer and Activator of Transcription 1-Mediated IFN Regulatory Factor 8 Activation in Colon Carcinoma Cells. Mol Cancer Res. 2008 Dec;6(12):1841-51.

179. Deininger SO, Ebert MPA, Fütterer A, Gerhard M, Röcken C. MALDI imaging combined with hierarchical clustering as a new tool for the interpretation of complex human cancers. J Proteome Res. 2008; 7 (12): 5230–5236

178. Kolfenbach S, Mönkemüller K, Röcken C, Malfertheiner P. Whipple's Disease: Magnification Endoscopy and Histological Characteristics. Endoscopy. 2008 Sep;40 Suppl 2:E112. Epub 2008 May 8.

177. Röcken C. Molekulare Targets beim Kolonkarzinom: VEGF, EGFR - was noch? Der Pathologe. 2008 Nov;29 Suppl 2:200-3.

176. Ivanauskas A, Hoffmann J, Jonaitis LV, Markelis R, Juozaityte E, Kupcinskas L, Lofton-Day C, Röcken C, Malfertheiner P. Distinct TPEF/HPP1 gene methylation patterns in gastric cancer indicate a field effect in gastric carcinogenesis. Dig Liver Dis. 2008 Dec;40(12):920-6. Epub 2008 Sep 16

175. Röcken C. Pathologie der Amyloidosen. Der Nephrologe. 2008; 3(4): 275-284

174. Yu J, Tao Q, Cheung KF, Jin H, Poon FF, Wang X, Li H, Cheng YY, Röcken C, Ebert MPA, Chan AT, Sung JJY. Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors. Hepatology. 2008 Aug;48(2):508-18.

173. Manke H, Röcken C. Akkreditierung in der Pathologie. Der Pathologe. 2008; Sep;29(5):388-402.

172. Gu P, Xing X, Tänzer M, Röcken C, Weichert W, Ivanauskas A, Pross M, Peitz U, Malfertheiner P, Schmid R, Ebert MPA. Frequent loss of TIMP-3 expression in progression of esophageal and gastric adenocarcinomas. Neoplasia. 2008; 10(6): 563-572

171. Wex T, Ebert MPA, Kropf S, Dierkes J, Schüttler K, Röcken C, Höcker M, Malfertheiner P. Gene polymorphisms of the NOD-2/CARD-15 gene and the risk of gastric cancer in Germany. Anticancer Res. 2008;28:757-762

170.  Pape UF, Jann H, Müller-Nordhorn J, Bockelbrink A, Berndt U, Willich SN, Koch M, Röcken C, Rindi G, Wiedenmann B. Prognostic relevance of a proposed TNM-classification system for gastroenteropancreatic neuroendocrine tumors of foregut origin.  Cancer 2008 July 15; 113(2): 256-65

169. Eriksson M, Schönland S, Bergner R, Hegenbart U, Lohse P, Schmidt H, Röcken C. Three German fibrinogen Aα-chain amyloidosis patients with the p.Glu526Val mutation. Virchows Arch. 2008 July; 453(1):25-31

168. Burgermeister E, Liscovitch M, Röcken C, Schmid RM, Ebert MPA. Caveats of caveolin-1 in cancer progression. Cancer Letters. 2008 Sep 18;268(2):187-201.

167. Qiao L, Dai Y, Gu Q; Chan KW, Ma J; Lan HY, Zou B, Röcken C, Ebert MPA, Wong BC. Loss of XIAP sensitizes colon cancer cells to PPARg independent anti-tumor effects of troglitazone and 15-PGJ2. Cancer Letters. 2008 Sep 18;268(2):260-71

166. Gräntzdörffer I, Carl-McGrath S, Ebert MPA, Röcken C. Proteomics of pancreatic cancer - a review. Pancreas. 2008; 36(4):329-336

165. Röcken C, Ketterlinus R, Ebert M. Application of proteome analysis to the assessment of prognosis and response prediticion in clinical oncology. Curr Cancer Drug Targets. 2008 Mar;8(2):141-5

164. Kozian A, Schilling T, Hedenstierna G, Röcken C, Fredén F, Maripuu E, Hachenberg T. One-Lung Ventilation Induces Persistent Hyperperfusion and Alveolar Damage in the Ventilated Lung - an Experimental Study. Br J Anaesthesia. 2008 Apr;100(4):549-59

163. Spuler S, Carl M, Zabojszcza J, Straub V, Bushby K, Moore S, Bähring S, Wenzel K, Vinkemeier U, Röcken C. Dysferlin-deficient muscular dystrophy features amyloidosis. Ann Neurology. 2008 Mar;63(3):323-8

162. Röcken C, Neumann U, Ebert M. Neue Wege zur Früherkennung, Prognoseabschätzung und Therapie maligner Tumoren des Gastrointestinaltrakts. Z. Gastroenterol. 2008 Feb;46(2):216-22



161. Goette A, Bukowska A, Lendeckel U, Erxleben M, Hammwöhner M, Strugala D, Pfeiffenberger J, Röhl FW, Huth C, Ebert MPA, Klein HU, Röcken C. Angiotensin II receptor blockade reduces tachycardia–induced atrial adhesion molecule expression. Circulation. 2008 Feb 12;117(6):732-42.

160.  Weichert W, Röske A, Gekeler V, Beckers T, Ebert MPA, Pross M, Dietel M, Denkert C, Röcken C. Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis. Lancet Oncol. 2008 Feb;9(2):139-48.

159. Röcken C, Ebert MPA. Postoperative staging of pancreatic cancer. Recent Results in Cancer Research. 2008;177:39-48.

158. Carl-McGrath S, Schneider-Stock R, Ebert M, Röcken C. Differential expression and localization of gasdermin-like (GSDML), a novel member of the cancer-associated GSDMDC protein family, in neoplastic and non-neoplastic gastric, hepatic and colon tissues. Pathology. 2008;40(1):13-24.

157. Csepregi A, Röcken C, Hoffmann J, Gu P, Saliger S, Müller O, Schneider-Stock R, Kutzner N, Roessner A, Malfertheiner P, Ebert MPA. APC promoter methylation and protein expression in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2008 May;134(5):579-89.


2007

156. Carl-McGrath, Ebert M, Röcken C. Gastric adenocarcinoma: epidemiology, pathology and pathogenesis. Cancer Therapy. 2007;5:879-896

155. Habicht G, Haupt C, Friedrich RP, Hortschansky P, Sachse C, Meinhardt J, Wieligmann K, Gellermann GP, Brodhun M, Götz J, Grigorieff N, Halbhuber KJ, Röcken C, Horn U, Fändrich M. Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Ab protofibrils. Proc. Natl. Acad. Sci. U.S.A. 2007;104(49):19232-7.

154. Carl-McGrath S, Ebert MPA, Lendeckel U, Röcken C. Expression of the local angiotensin II system in gastric cancer may facilitate lymphatic invasion and nodal spread. Cancer Biol Ther. 2007; 6(8) [Epub ahead of print]

153. Ebert MP, Schmid R, Röcken C. Need for a paradigm shift in cancer prevention and clinical oncology. Expert Rev Anticancer Ther. 2007 Oct;7(10):1363-7

152. Röcken C, Neumann K, Carl-McGrath S, Lage H, Ebert MPA, Dierkes J, Jacobi CA, Kalmuk S, Neuhaus P, Neumann U. The Gene Polymorphism of the Angiotensin I-Converting Enzyme correlates with Tumor Size and Patient Survival In Colorectal Cancer Patients. Neoplasia. 2007; 9(9):716-22

151. Röcken C, Neumann U. Anatomie der Leber und Pathologie der Lebertumoren. Viszeralchirurgie. 2007; 42:215-222

150.  Burgermeister E, Xing X, Röcken C, Juhasz M, Chen J, Hiber M, Mair K, Shatz M, Liscovitch M, Schmid RM, Ebert MP. Differential expression and function of caveolin-1 in human gastric cancer progression. Cancer Res. 2007; 67(18): 8519-26

149. Treiber G, Röcken C, Wex T, Malfertheiner P. Octreotide Alone or in Combination with Rofecoxib as Palliative Treatmentfor Advanced Hepatocellular Cancer. Z Gastroenterol. 2007;45(5):369-77

148. Bellutti M, Weigt J, Mönkemüller K, Röcken C, Wieners G, Dombrowski F, Malfertheiner P. Localized primary AL-type amyloidosis of the jejunum diagnosed by double-balloon enteroscopy. Endoscopy. 2007 Feb;39 Suppl 1:E134-5. Epub 2007 Jul 9.

147. Röcken C, Röhl FW, Diebler E, Lendeckel U, Pross M, Carl-McGrath S, Ebert MPA. The angiotensin II/angiotensin II receptor system correlates with nodal spread in intestinal type gastric cancer. Cancer Epidemiol Biomarkers Prev. 2007; 16(6):1206-12



146. Ebert M, Xing X, Burgermeister E, Schmid R, Röcken C. Perspectives of clinical proteomics in gastrointestinal cancer. Exp Rev Anticancer Ther. 2007 Apr;7(4):465-469.

145. Ebert MP, Röcken C. First Steps Towards Molecular Prevention in Gastric Carcinogenesis. Cancer Biol Ther. 2007 Feb;6(2):276-7.

144. Götte A, Lendeckel U, Kuchenbecker A, Bukowska A, Peters B, Klein HU, Huth C, Röcken C. Cigarette smoking induces via nicotine atrial fibrosis. Heart. 2007;93(9):1056-63.

143. Preller V, Gerber A, Wrenger S, Togni M, Marguet D, Tadje J, Lendeckel U, Röcken C, Faust J, Neubert K, Schraven B, Martin R, Ansorge S, Brocke S, Reinhold D. TGF-beta.1-mediated control of CNS inflammation and autoimmunity through the inhibitory receptor CD26. J Immunol. 2007;178(7):4632-40

142. Kuci H, Ebert MPA, Röcken C. Anti-lambda-light chain-peptide antibodies are suitable for the immunohistochemical classification of AL amyloid. Histol Histopathol. 2007; 22(4):379-87

141. Mönkemüller K, Fry LC, Ebert M, Bellutti M, Venerito M, Knippig C, Rickes S, Muschke P, Röcken C, Malfertheiner P. Feasibility of double-balloon enteroscopy-assisted chromoendoscopy of the small bowel in patients with familial adenomatous polyposis. Endoscopy. 2007; 39:52-57

140.  Schulz HU, Kellner U, Kahl S, Effenberger O, Asperger W, Lippert H, Röcken C. A giant pancreatic serous microcystic adenoma with 20 years follow-up. Langenbeck's Archives of Surgery. 2007;392(2):209-13

139. Götze T, Röcken C, Röhl FW, Wex T, Hoffmann J, Westphal S, Malfertheiner P, Ebert MPA, Dierkes J. Gene polymorphisms of folate metabolizing enzymes and the risk of gastric cancer. Cancer Letters. 2007 Jun 28;251(2):228-36

138. Obermeyer K, Krüger S, Peters B, Falkenberg B, Roessner A, Röcken C. The Expression of Low Density Lipoprotein Receptor-related Proteins (LRP) in colorectal cancer. Oncol Reports. 2007;17(2):361-7


2006

137. Röcken C, Ernst J. Amyloiddiagnostik bei rheumatischen Erkrankungen. Pathologe. 2006 Nov;27(6):422-30

136. Ebert M, Meyer L, Röcken C. Magen. In: Kahl et al. (Hrsg.) Interventionelle Endoskopie. Lehrbuch und Atlas. Elsevier GmbH, München, 2006

135. Röcken C, Ernst J, Hund E, Michels H, Perz J, Saeger W, Sezer O, Spuler S, Willig F, Schmidt HHJ. Interdisziplinäre Leitlinien zur Diagnostik und Therapie der extrazerebralen Amyloidosen. Med Klin. 2006 Oct 15;101(10):825-9.

134. Röcken C, Fändrich M, Stix B, Tannert A, Hortschansky P, Reinheckel T, Saftig P, Kähne T, Menard R, Ancsin JB, Bühling F. Cathepsin protease activity modulates amyloid-load in extracerebral amyloidosis. J Pathol. 2006 Dec;210(4):478-87

133. Ebert MPA, Model F, Mooney S, Hale K, Lograsso K, Tonnes-Priddy L, Hoffmann J, Csepregi A, Röcken C, Schulz HU, Malfertheiner P, Lofton-Day C. Genome scanning analysis identifies ALX4 gene methylation as a potential marker for colorectal and other gastrointestinal adenocarcinomas. Gastroenterology. 2006 Nov;131(5):1418-30

132. Ebert MPA, Niemeyer D, Deininger  SO, Wex T, Knippig C, Hoffmann J,  Sauer J, Albrecht W, Malfertheiner P, Röcken C. Identification of increased fibrinopeptide A serum protein levels in gastric cancer sera by magnet bead assisted MALDI-TOF mass spectrometry. J Protome Res. 2006;5(9):2152-2158

131. Carl-McGrath, Lendeckel U, Ebert M, Röcken C. Ectopeptidases in tumour biology: a review. Histol Histopathol. 2006;21(12):1339-53

130.  Ebert MPA, Yu J, Röcken C. Proteomics in gastroinestinal cancers. Ann Oncol. 2006; Suppl. 10:x253-x258

129. Schulz S, Röcken C, Schulz S. Immunohistochemical detection of bombesin receptor subtypes GRP-R and BRS-3 in human tumors using novel anti-peptide antibodies. Virchows Arch. 2006; 449:421-427

128. Schulz S, Röcken C, Ebert MP, Schulz S. Immunocytochemical identification of low-affinity NTS2 neurotensin receptors in parietal cells of human gastric mucosa. J Endocrinol. 2006 Oct;191(1):121-8

127. Schulz S, Röcken C, Schulz S. Immunocytochemical localization of plasma membrane GHRH receptors in human tumors. Frequent expression in breast, ovarian and prostate carcinoma. Eur J Cancer. 2006;42(14):2390-6

126. Röcken C, Ernst J, Hund E, Michels H, Perz J, Saeger W, Sezer O, Spuler S, Willig F, Schmidt HHJ. Interdisziplinäre Leitlinien zur Diagnostik und Therapie der extrazerebralen Amyloidosen. Dtsch Med Wochenschr. 2006;131 Suppl 2:S45-66

125. Röcken C. Extrazerebrale Amyloidose – erste umfassende Leitlinie. Dtsch Med Wochenschr. 2006;131 Suppl 2:S44

124. Treiber G, Wex T, Röcken C, Fostitsch P, Malfertheiner P. Impact of biomarkers on disease survival and progression in patients treated with octreotide for advanced hepatocellular carcinoma. J Cancer Res Clin Oncol. 2006;132(11):699-708

123. Ebert MP, Röcken C. Molecular screening of gastric cancer by proteome analysis. Eur J Gastroenterol Hepatol. 2006;18:847-53

122. Daigeler A, Kuci H, Altmann S, Schneider W,  Röcken C
Extramedullary multiple myeloma associated with amyloidomas of the lower limb.
Plast Reconstr Surg. 2006;117:2530-2

121. Kebbel A, Röcken C. Immunohistochemical classification of amyloid revisited. Am J Surg Pathol. 2006;30:673-83.

120. Preller V, Gerber A, Togni M, Wrenger S, Schraven B, Röcken C, Marguet D, Ansorge S, Brocke S, Reinhold D. CD26/DP IV in T cell activation and autoimmunity. Adv Exp Med Biol. 2006;575:187-93.

119. Schulz S, Stumm R, Röcken C, Mawrin C, Schulz S. Immunolocalization of full-length NK1 tachykinin receptor in human tumors. J Histochem Cytochem. 2006; 54(9):1015-20

118. Csepregi A, Röcken C, Treiber G, Malfertheiner P. Budesonide in autoimmune hepatitis.World J Gastroenterol. 2006; 12:1362-1366

117. Qiao L, Zhang H, Yu J, Francisco R, Dent P. Ebert MPA, Röcken C, Farrell G. Constitutive Activation of NF-kB in Human Hepatocellular Carcinoma: Evidence of a Cytoprotective Role. Human Gene Therapy. 2006; 17:280-290

116. Röcken C, Ebert MPA. Pancreatic Cancer Proteome. Gastroenterology. 2006; 130:1017

115. Röcken C, Tautenhahn J, Bühling F, Sachwitz D, Vöckler S, Goette A, Bürger T. Prevalence and pathology of amyloid in atherosclerotic arteries. Arteriosclerol Thromb Vasc Biol. 2006; 26:676-7



114. Mönkemüller K, Weigt J, Treiber G, Kolfenbach S, Kahl S, Röcken C, Ebert M, Fry LC Malfertheiner P. Diagnostic and therapeutic impact of double-balloon enteroscopy. Endoscopy. 2006; 38:67-72

113. Ebert MPA, Korc M, Malfertheiner P, Röcken C. Advances, challenges and limitations in serum-proteome based cancer-diagnosis. J Proteome Res. 2006 Jan;5(1):19-25

112. Yu J, Qiao L, Zimmermann L, Francisco R, Ebert MPA, Röcken C, Lin W, Teoh N, Malfertheiner P, Farrell GC. Troglitazone inhibits tumor growth in hepatocellular carcinoma in vitro and in vivo. Hepatology. 2006;43:134-43

111. Röcken C, Becker K, Fändrich M, Schroeckh V, Stix B, Rath T, Kähne T, Dierkes J, Roessner A, Albert FW. ALys amyloidosis caused by compound heterozygosity in exon 2 (Thr70Asn) and exon 4 (Trp112Arg) of the lysozyme gene. Hum Mutation. 2006 Jan;27(1):119-20

110.  Chen J, Röcken C, Nitsche B, Hosius C, Gschaidmeier H, Kahl S, Malfertheiner P, Ebert MPA. The tyrosine kinase inhibitor imatinib fails to inhibit pancreatic cancer progression. Cancer Lett. 2006 Feb 28; 233(2):328-37


2005

109. Ebert MPA, Lendeckel U, Dierkes J, Folwaczny C, Roessner A, Stolte M, Malfertheiner P,  Röcken C. The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer. Cancer Epidemiol Biomarkers Prev. 2005;14:2987-9

108. Röcken C, Wilhelm S. Influence of tissue fixation  on the extraction and identification of amyloid proteins. J Lab Clin Med. 2005; 146:244-250

107. Gregorini G, Izzi C, Obici L, Tardanico R, Röcken  C, Viola BF, Capistrano M, Donadei S, Biasi L, Scalvini T, Merlini G, Scolari F. Renal Apolipoprotein A-I Amyloidosis: A Rare Cause of Hereditary Tubulo-Interstitial Nephritis. J Am Soc Nephrol. 2005; 16:3680-6

106. Ebert MPA, Mooney S, Tonnes-Priddy L, Lograsso J, Chen J, Röcken  C, Schulz HU, Malfertheiner P, Lofton-Day C. Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancer. Neoplasia. 2005;7:771-778

105. Foitschik T, Saeger W, Riebe M, Röcken C. Advanced glycation end products in intervertebral discs and hip joint capsules: Correlation to senile amyloid? Amyloid. 2005; 12:167-73

104. Röcken C, Licht J, Roessner A, Carl-McGrath S. Canalicular immunostaining of aminopeptidase N (CD13) as a diagnostic marker for hepatocellular carcinomas. J Clin Pathol. 2005; 58:1069-1075

103. Schulz S, Röcken C, Mawrin C, Schulz SImmunocytochemical localization of CCK1 Cholecystokinin Receptors in Normal and Neoplastic Human Tissues. J Clin Endocrinol Metab. 2005; 90: 6149-55

102. Ochel HJ, Gademann G, Röcken C, Wördehoff H. Effects of Imatinib Mesylate on Adenoid Cystic Carcinomas. Anticancer Research. 2005; 25:3659-3664

101. Ebert MPA, Schäfer C, Chen J, Hoffmann J, Gu P, Kubisch C, Carl-McGrath S, Treiber G, Malfertheiner P,  Röcken C. Protective Role of Heat Shock Protein 27 in Gastric Mucosal Injury. J Pathol. 2005; 207:177-184

100.  Krüger S, Kalinski T, Hundertmark T, Wolf H, Wex T, Peitz U, Nägler D, Malfertheiner P, Naumann M, Röcken C, Roessner A. Up-regulation of cathepsin X in H. pylori-gastritis and gastric cancer. J Pathol. 2005; 207:32-42

99. Eder F, Schulz HU, Röcken C, H Lippert. A case of solid-pseudopapillary tumor of the pancreatic tail. World J Gastroenterol. 2005; 11:4117-4119

98. Csepregi A, Treiber G, Röcken C, Malfertheiner P. Acute exacerbation of autoimmune hepatitis induced by Twinrix. World J Gastroenterol. 2005; 11: 4114-4116

97. Linke RP, Joswig R, Murphy CL, Wang S, Zhou H, Gross U, Röcken C, Westermark P, Weiss DT, Solomon A. Senile seminal vesicle amyloid is derived from semenogelin I. J Lab Clin Med. 2005; 145: 187-193

96. Chen J, Röcken C, Hoffmann J, Krüger S, Lendeckel U, Rocco A, Pastorekova S, Malfertheiner P, Ebert MPA. Expression of carbonic anhydrase IX (CA9) at the invasion front of gastric cancer. Gut. 2005; 54:920-927

95. Röcken C, Menard R, Bühling F, Vöckler S, Raynes J, Stix B, Krüger S, Roessner A, Kähne T. Proteolysis of serum amyloid A and AA amyloid proteins by cysteine proteases: cathepsin B generates AA amyloid proteins and cathepsin L might prevent their formation. Ann Rheum Dis. 2005; 64: 808-815

94. Gellermann GP, Appel TR, Tannert A, Radestock A, Hortschanski P, Schroeckh V, Leisner C, Lütkepohl T, Sthrasburg S, Röcken C, Pras M, Linke RP, Diekmann S, Fändrich M . Raft lipids as novel and common components of human, extracellular amyloid fibrils. Proc. Natl. Acad. Sci. U.S.A. 2005;102: 6297-302

93. Bühling F, Wille A, Röcken C, Wiesner O, Welte T, Pap T. Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis. Respiratory Res. 2005;6:37

92. Ebert MPA, Lamer S, Meuer  J, Malfertheiner P, Buschmann T, Röcken  C, Seibert V
Identification of the thrombin light chain A as the single best mass for differentiation of gastric cancer patients from individuals with dyspepsia by proteome analysis. J Proteome Res. 2005; 4: 586-590

91. Röcken C, Lendeckel U, Dierkes J, Westphal J, Carl-McGrath S, Peters B, Krüger S, Malfertheiner P, Roessner A, Ebert MPA. The number of lymph node metastases in gastric cancer correlates with the angiotensin I-converting enzyme gene insertion/deletion polymorphism. Clin Cancer Res. 2005; 11: 2526-2530

90.  Stix B, Leber M, Bingemer P, Gross C, Rüschoff J, Fändrich M, Schoderet D, Vorwerk C, Zacharias M, Roessner A, Röcken C. Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of kerato-epithelin. Invest Ophthalmol Vis Sci. 2005; 46:1133-1139

89. Ebert M, Krüger S, Fogeron ML, Lamer S, Chen J, Pross M, Schulz HU, Lage H, Heim S, Roessner A, Malfertheiner P, Röcken C. Overexpression of Cathepsin B in gastric cancer identified by proteome analysis. Proteomics. 2005; 5:1693-704

88. Lendeckel U, Müller C, Röcken C, Laube B, Täger M, Huth C, Klein HU, Goette A. Expression of opioid receptor subtypes and their ligands in fibrillating human atria. PACE Suppl. 2005; 28: S275-S279

87. Evert M, Wardelmann E, Nestler G, Schulz HU, Roessner A, Röcken C. Abdominopelvic perivascular epithelioid cell sarcoma (malignant PEComa) with expression of c-kit (CD117). Histopathology. 2005; 46:108-117

86. Carl-McGrath S, Lendeckel U, Ebert M, Roessner A, Röcken C. The disintegrin-metalloproteinases ADAM-9, ADAM-12, and ADAM-15 are upregulated in gastric cancer. Int J Oncol. 2005; 26(1):17-24

85. Lendeckel U, Kohl J, Arndt M, Carl-McGrath S, Donat H, Röcken C. Increased expression of ADAM family members in human breast cancer and . breast cancer cell lines. J Cancer Res Clin Oncol. 2005; 131:41-48

84. Koester MO, Pross M, Dormann A, Röcken C, Lippert H, Huchzermeyer H. Multiple Rundherde der Leber bei einer 33-jährigen Patientin - Falldarstellung einer ungewöhnlichen Differentialdiagnose. Internist. 2005;46(1):69-74

83. Chen J, Röcken C, Lofton-Day C, Schulz HU, Müller O, Kahmann S, Malfertheiner P, Ebert MPA. Molecular analysis of APC promoter methylation and protein expression in colorectal cancer metastasis. Carcinogenesis. 2005; 26:37-43


2004

82. Chen J, Röcken C, Malfertheiner P, Ebert MPA. Recent advances in molecular diagnosis and therapy of gastric cancer. Dig Dis. 2004; 22: 380-385

81. Götze T, Schütte K, Röcken C, Malfertheiner P, Ebert MPA. Recent developments in chemotherapy of advanced gastric cancer. Dig. Dis. 2004; 22:360-365

80.  Ebert MPA, Meuer J, Wiemer J, Schulz HU, Reymond M, Traugott U, Malfertheiner P, Röcken C. Identification of gastric cancer patients by serum protein profiling. J Proteome Res. 2004; 3: 1261-1266

79. Schulz S, Röcken C, Mawrin C, Weise W, Höllt V, Schulz S. Immunocytochemical ientification of VPAC1, VPAC2 and PAC1 receptors in normal and neoplastic human tissues using subtype-specific antibodies. Clin Cancer Res. 2004; 10: 8235-8242

78. Chen J, Röcken C, Klein-Hitpass, Malfertheiner P, Ebert MPA. Microarray analysis of gene expression in metastatic cancer cells exposed to the methylation inhibitor 5-aza-2′-deoxycytidine. Clin Exp Metastasis. 2004; 21: 389-397

77. Chen J, Kähne T, Röcken C, Götze T, Yu J, Sung JJY, Chen M, Hu P, Malfertheiner P,. Ebert MPA. Proteome analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasis-related proteins. J Proteome Res. 2004; 3:1009-1016

76. Carl-McGrath S, Lendeckel U, Ebert M, Wolter AB, Roessner A, Röcken C. The ectopeptidases CD10, CD13, CD26, and CD143 are upregulated in gastric cancer. Int J Oncol. 2004; 25: 1223-1232

75. Bühling F, Röcken C, Brasch F, Hartig R, Yasuda Y, Saftig P, Brömme D, Welte T. Pivotal role of cathepsin K in the prevention of lung fibrosis. Am J Pathol. 2004; 164: 2203-2216

74. Waldburg N, Kähne T, Reisenauer A, Röcken C, Welte T, Bühling F. Clinical proteomics in lung disease. Path Res Pract. 2004; 200: 69-82

73. Bohne S, Sletten K, Menard R, Bühling F, Vöckler S, Wrenger E, Roessner A, Röcken C. Cleavage of AL amyloid proteins by Cathepsin B, K and L. J Pathol. 2004; 203:528-537

72. Röcken C, Carl-McGrath S, Gräntzdörffer I, Mantke R, Roessner A, Lendeckel U. Ectopeptidases are differentially expressed in hepatocellular carcinomas. Int J Oncol. 2004; 24:487-495

71. Gräntzdörffer I, Lendeckel U, Carl-McGrath S, Roessner A, Röcken C. Angiotensin I-converting enzyme (CD 143) is down-regulated in focal nodular hyperplasia of the liver. Am J Surg Pathol. 2004: 28: 84-88

70.  Evert M, Roessner A, Röcken C. Synchronous granulomatous cholecystitis and fibroelastosis of the gallbladder. Virchows Archiv. 2004; 445(6): 655-658

69. Mahlfeld K, Graßhoff H, Jentsch-Ullrich K, Röcken C, Franke J. Sonographischer Nachweis einer Osteolyse bei solitärem Plasmozytom des Sternums. Zentralbl Chir. 2004; 129(1):63-66

68. Götte A, Röcken C . Atrial amyloidosis and atrial fibrillation: A gender-dependent "arrhythmogenic substrate"? Eur Heart J. 2004; 25:1185-1186

67. Röcken C, Ebert MPA, Roessner A. Proteomics in Pathology Research and Practice. Path Res Pract. 2004; 200(2): 69-82

66. Röcken C. Proteomics in Pathology Research and Practice. Path Res Pract. 2004; 200(2): 67-67




2003

65. Chen J, Röcken C, Treiber G, Jentsch-Ulrich K, Malfertheiner P, Ebert MPA. Clinical implications of alpha-fetoprotein expression in gastric adenocarcinoma. Dig. Dis. 2003; 21: 358-362

64. Götte A, Jentsch-Ullrich K, Lendeckel U, Röcken C, Agbaria M, Mohren M, Auricchio A, Mohren M, Franke A, Klein HU. Effect of atrial fibrillation on hematopoietic progenitor cells. A novel pathophysiologic role of the atrial natriuretic peptide? Circulation. 2003; 108:2446-2449

63. Vogt S, Schneider-Stock R, Klauck S, Roessner A, Röcken C. Detection of hepatitis C virus RNA in formalin-fixed, paraffin embedded thin needle liver biopsies specimens. Am J Clin Pathol. 2003; 120(4):536-543

62. Juhasz M, Ebert MPA, Schulz HU, Röcken C, Molnar B, Tulassay Z, Malfertheiner P. Dual role of serum soluble E-cadherin as an indicator of metastatic development in gastric cancer. Scand J Gastroenterol. 2003; 38:850-855

61. Ebert MPA, Ju Y, Hoffmann J, Rocco A, Röcken C, Kahmann S, Müller O, Korc M, Sung JJ, Malfertheiner P. Loss of b-catenin expression in metastatic gastric cancer. J Clin Oncol. 2003; 21(9):1708-1714

60.  Röcken C, Kientsch-Engel R, Mansfeld S, Stix B, Schwan M, Stubenrauch K, Weigle B, Bühling F, Schwan M, Saeger W. Advanced glycation end products in AA amyloidosis. Am J Pathol. 2003; 162:1213-1220

59. Petz D, Klauck S, Röhl FW, Malfertheiner P, Roessner A, Röcken C. Feasibility of histological grading and staging of chronic viral hepatitis using specimens obtained by thin needle biopsy. Virchows Archiv. 2003; 442:238-244

58. Mawrin C, Brunn A, Röcken C, Schröder JM. Peripheral neuropathy in systemic lupus erythematosus: pathomorphological features and distrubtuion pattern of matrix metalloproteinases. Acta Neuropathologica. 2003; 105:365-372

57. Kellner U, Jacobsen A, Kellner A, Mantke R, Roessner A, Röcken C. Comparative genomic hybridization: Synchronous occurrence of focal nodular hyperplasia and hepatocellular carcinoma in the same liver is not based on common chromosomal aberrations. Am J Clin Pathol. 2003; 119:265-271

56. Chen J, Chen M, Röcken C, Götze T, Malfertheiner P, Ebert MPA. Molecular therapy of gastric cancer. Cancer Therapy 2003; 12(1): 321-331

55. Fels L, Buschmann T, Meuer J, Raymond MA, Lamer S, Röcken C, Ebert M. Proteome analysis for the identification of tumor-associated biomarkers in gastrointestinal cancer. Dig Dis. 2003; 21:292-298

54. Röcken C, Sletten K. Amyloid in surgical pathology. Virchows Archiv. 2003; 443:3-16

53. Götte A, Röcken C, Nepple K, Lendeckel U. Proteases and Arrhythmias.. In: Lendeckel U, Hooper NM (Hrsg.) Proteases in biology and disease. Proteases in tissue remodeling of lung and heart. Kluwer-Academic/Plenum Publishers, New York, 2003; S. 191-218

52. Peitz U, Röcken C. Lebererkrankungen bei Alpha-1 Antitrypsinmagel. In: Alpha-1 Antitrypsinmangel. Referenz für Klinik und Praxis. In: Köhlein T, Welte T (Hrsg.) UNI-MED, Bremen, 2003; S. 40-45


2002 - 1992

51. Röcken C, Peters B, Juenemann G, Saeger W, Klein HU, Huth C, Roessner A, Goette A. Atrial amyloidosis: An arrhythmogenic substrate for persistent atrial fibrillation. Circulation. 2002; 106:2091-2097



50.  Bühling F, Waldburg N, Krüger S, Röcken C, Wiesner O, Weber E, Welte T. Expression of cathepsins B, H, K, L, and S during human fetal lung development. Dev. Dyn. 2002; 225:14-21

49. Mantke R, Röcken C, Schubert D, Pross M, Sokolowski A, Halangk W, Lippert H, Schulz HU. Enzymatic and histological alterations in the isolated perfused rat pancreas under conditions of oxidative stress. Langenbecks Arch Surg. 2002; 387:170-176

48. Götte A, Arndt M, Röcken C, Staack T, Bechtloff R, Reinhold D, Huth C, Ansorge S, Klein HU, Lendeckel U. Calpains and cytokines in fibrillating human atria. Am J Physiol. 2002; 283:H264-H272

47. Röcken C, Kronsbein H, Sletten K, Roessner A, Bässler R. Amyloidosis of the breast. Virchows Archiv. 2002; 440:527-535

46. Götte A, Juenemann G, Klein HU, Peters B, Roessner A, Huth C, Röcken C. Determinants and consequences of atrial fibrosis in patients undergoing open heart surgery. Cardiovascular Res. 2002; 54:390-396

45. Arndt M, Lendeckel U, Röcken C, Nepple K, Wolke C, Spiess A, Huth C, Ansorge S, Klein HU, Goette A. Altered expression of ADAMs (a disintegrin and metalloproteinase) in fibrillating human atria. Circulation. 2002; 105:720-725

44. Wieker K, Röcken C, Koenigsmann M, Roessner A, Franke A. MALT-lymphoma and pulmonary amyloidosis. A case report. Amyloid. 2002; 9:190-193

43. Knippig C, Röcken C, Roessner A, Neumann W, Malfertheiner P. Schultermetastase als Erstmanifestation eines hepatozellulären Karzinoms (HCC). Med Klinik. 2002; 97:361-364

42. Wrenger E, Röcken C, Dietzmann J, Grote HJ, Roessner A, Neumann KH. Ambulatory treatment with intravenous norepinephrine in a patient with end stage renal failure and generalized AA amyloidosis. Amyloid. 2002; 9:47-51

41. Röcken C. Differentialdiagnose der Amyloidose. Verh Dtsch Ges Path. 2002; 86:107-115

40.  Röcken C. 16th Amyloidforum organized by the German Society of Amyloid Diseases, April 2002 in Vienna, Austria. Amyloid. 2002; 9:207-211

39. Röcken C, Shakespeare A. Pathology, diagnosis, and pathogenesis of AA amyloidosis.. Virchows Archiv. 2002; 440:111-122

38. Röcken C, Meier H, Klauck S, Wolff S, Malfertheiner P, Roessner A. Large needle biopsy versus thin needle biopsy in diagnostic pathology of liver diseases. Liver. 2001; 21:391-397

37. Schubert D, Mantke R, Pross M, Röcken C, Sokolowski A, Halangk W, Lippert H, Schulz HU. Enzymatische und histologische Veränderungen am isoliert perfundierten Pankreas der Ratte im Taurocholat- und Cerulein-Modell der akuten Pankreatitis. Zentralbl Chir. 2001; 126:934-938

36. Borscheri N, Roessner A, Röcken C. Canalicular immunostaining of neprilysin (CD10) as a diagnostic marker of hepatocellular carcinomas. Am J Surg Pathol. 2001; 25:1297-1303

35. Bühling F, Reisenauer A, Gerber A, Krüger S, Weber E, Brömme D, Roessner A, Ansorge S, Welte T, Röcken C. Cathepsin K - a marker of macrophage differentiation? J Pathol. 2001; 195:375-382

34. Stix B, Kähne T, Sletten K, Raynes J, Roessner A, Röcken C. Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1, -2, and –3. Am J Pathol. 2001; 159:561-570

33. Mantke R, Ridwelski K, Röcken C, Pross M, Schulz HU, Lippert H. Das hepatobiliäre Zystadenom. Chirurg. 2001; 72:277-280

32. Röcken C, Stix B, Brömme D, Ansorge S, Roessner A, Bühling F. A putative role for cathepsin K in degradation of AA and AL amyloidosis. Am J Pathol. 2001; 158:1029-1038

31. Röcken C, Carl-McGrath S. Pathology and pathogenesis of hepatocellular carcinoma.. Dig Dis. 2001; 19:269-278

30.  Müller D, Roessner A, Röcken C. Distribution pattern of  matrix metalloproteina­ses (MMP-1, -2, -3, and -9), tissue inhibitors of matrix metalloproteinases (TIMP-1 and -2), and a2-macroglobulin in cases of generalized AA and AL amyloidosis. Virchows Arch. 2000; 437:521-527

29. Steusloff K, Röcken C, Saeger W. Basement membrane proteins and apolipoprotein E in growth hormone secreting adenomas and their correlation to amyloid: an immunoelectron microscopic study. Endocr Pathology. 2000; 11:49-56

28. Götte A, Arndt M, Röcken C, Staack T, Geller JC, Huth C, Ansorge S, Klein HU, Lendeckel U. Regulation of angiotensin II receptor subtypes during atrial fibrillation. Circulation 2000; 101:2678-269

27. Götte A, Staack T, Röcken C, Arndt M, Geller JC, Huth C, Ansorge S, Klein HU, Lendeckel U . Increased expression of extracellular-signal regulated kinases and angiotensin-converting enzyme in human atria during atrial fibrillation. J Am Coll Cardiol 2000; 35:1669-1677

26. Röcken C, Hegenbarth V, Schmitz M, Stix B, Schade G, Mohnert A, Roessner A. Plasmacytoma of the tonsil with secondary AL amyloidosis and osseous metaplasia. Virchows Archiv. 2000;  436(4):336-344

25. Pap G, Eberhardt R, Röcken C, Nebelung W, Neumann HW, Roessner A. Expression of stromelysin and urokinase type plasminogen activator protein in resection specimens and biopsies at different stages o osteoarthritis of the knee. Path Res Pract. 2000; 196:219-226

24. Bässler R, Würstlein R, Röcken C, Christ F. Tumorförmige bilaterale Amyloidose der Mamma assoziiert mit einem invasiven lobulären Karzinom und Sjögren-Syndrom. Kasuistik und Literaturübersicht. Geburtshilfe und Frauenheilkunde. 2000; 60:645-650

23. Röcken C, Pross M, Brucks U, Ridwelski C, Roessner A. Cholangiocarcinoma occurring in a liver with multiple bile duct hamartomas (von Meyenburg complexes). Arch Pathol Lab Med. 2000; 124:1704-1706

22. Röcken C, Wieker K, Grote HJ, Müller G, Franke A, Roessner A. Rosai-Dorfman disease and generalized AA amyloidosis. A case report. Hum Pathol. 2000; 31(5):621-624



21. Röcken C, Roessner A. An evaluation of antigen retrieval procedures for immunoelectron microscopical classification of amyloid deposits.. J Histochem Cytochem. 1999; 47:1385-94

20.  Röcken C, Schneider-Stock R, Buhtz P, Manger T, Roessner A. Hepatic angiomyolipoma in a 26-year-old Caucasian woman with a history of tibial osteosarcoma. Path Res Pract. 1999; 195:765-772

19. Röcken C, Radun D, Glasbrenner B, Malfertheiner P, Roessner A. Generalized AA-amyloidosis in a 58-year-old Caucasian woman with an 18-month history of gastrointestinal tuberculosis. Virchows Archiv. 1999; 434:95-100

18. Mohr A, Miehlke S, Klauck S, Röcken C, Malfertheiner P. Hepatomegaly and cholestasis as primary clinical manifestation of an AL-kappa amyloidosis. Eur J Gastroenterol Hepatol. 1999; 11:921-925

17. Glasbrenner B, Güthner C, Röcken C, Mattfeld T, Hetzel W, Adler G. 56jähriger Patient mit segmental florider Colitis und Colonamyloidose. Internist. 1999; 40:668-672

16. Steusloff K, Röcken C, Saeger W. Basement membrane proteins, apolipoprotein E and glycosaminoglycans in pituitary adenomas and their correlation to amyloid. Virchows Archiv. 1998; 433:29-34.

15. Röcken C, Kisilevsky R. Comparison of the binding and endocytosis of high-density lipoprotein from healthy (HDL) and inflamed (HDLSAA) donors by murine macrophages of four different mouse strains. Virchows Archiv. 1998; 432:547-555

14. Saeger W, Röcken C. Amyloid: Mikroskopischer Nachweis, Klassifikation und klinischer Bezug. Pathologe. 1998; 19:345-354

13. Röcken C, Kisilevsky R. Binding and endocytosis of murine high density lipoprotein from healthy (HDL) and inflamed donors (HDLSAA) by murine macrophages in vitro. A light- and electronmicroscopic investigation. Amyloid. 1997; 4:259-273

12. Röcken C, Paris D, Steusloff K, Saeger W. Investigation of the presence of apolipoprotein E, glycosaminoglycans, basement membrane proteins, and protease inhibitors in senile interstitial amyloid of the pituitary. Endocr Pathol. 1997; 8:205-214

11. Röcken C, Schwotzer E, Linke RP, Saeger W. The classification of amyloid deposits in clinicopathological practice. Histopathology. 1996; 29:325-335

10.  Röcken C, Eick B, Saeger W. Senile amyloidoses of the pituitary and adrenal glands. Morphological and statistical investigations. Virchows Arch. 1996; 429:293-299

9. Röcken C, Saeger W, Linke RP. Portal amyloid. Novel amyloid deposits in gastrointestinal veins? Arch Pathol Lab Med. 1996; 120:1044-1051

8. Röcken C, Linke RP, Saeger W. Corpora amylacea in the lung, prostate and uterus: A comparitive immunohistochemical study. Path Res Pract. 1996; 192:998-1006

7. Röcken C, Saeger W, Fleege JC, Linke RP. Interstitial amyloid deposits in the pituitary gland: Morphometry, immunohistology, and correlation to diseases. Arch Pathol Lab Med. 1995; 119:1055-1060

6. Röcken C, Uhlig H, Saeger W, Linke RP, Fehr S. Amyloid deposits in pituitaries and pituitary adenomas: Immunohistochemistry and in situ hybridization. Endocr Pathol. 1995; 6:135-143

5. Röcken C, Saeger W, Linke RP. Gastrointestinal amyloid deposits in old age. Report on 110 consecutive autopsical patients and 98 retrospective bioptic specimens. Path Res Pract. 1994; 190:641-649

4. Röcken C, Saeger W. Amyloid deposits of the pituitary in old age: Correlation with histopathological alterations. Endocr Pathol. 1994; 5:183-190

3. Saeger W, Röcken C, Linke RP. Amyloiddiagnostik in der klinischen Pathologie. HÄB. 1993; 1:9-14

2. Röcken C, Saeger W, Linke RP. Mehrere unterschiedliche Amyloidtypen bei einer 93-jährigen Patientin: Kasuistik eines Sektionsfalles.. Pathologe. 1993; 14:42-46

1. Röcken C, Linke RP, Saeger W. Immunohistology of islet amyloid polypeptide in diabetes mellitus: semiquantitative studies in a post-mortem series. Virchows Archiv [A]. 1992; 421:339-344